Protonix and Ticagrelor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Ticagrelor (ticagrelor). Common drug interactions include dyslipidaemia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Protonix and Ticagrelor. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

What is Ticagrelor?

Ticagrelor has active ingredients of ticagrelor. eHealthMe is studying from 8,499 Ticagrelor users. Check the latest studies of Ticagrelor.



On Jul, 30, 2026

35 people who take Protonix and Ticagrelor together, and have interactions are studied.

Protonix and Ticagrelor drug interactions.

What are the common drug interactions of Protonix and Ticagrelor, by gender? *:

female:

  1. Dyslipidaemia (abnormal amount of lipids)
  2. Dyspepsia (indigestion)
  3. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  4. Emotional disorder
  5. Eructation (release of gas from the digestive tract)
  6. Facet joint syndrome (problem with movement of the facet joints of the spine)
  7. Fatigue (feeling of tiredness)
  8. Flatulence (flatus expelled through the anus)
  9. Headache (pain in head)
  10. Herpes simplex (herpes simplex is a common viral infection)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Abdominal pain upper
  4. Atelectasis (partial or complete collapse of the lung)
  5. Body temperature decreased
  6. Brain natriuretic peptide increased
  7. Cardiac failure congestive
  8. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  9. Diarrhoea
  10. Drug administration error

What are the common drug interactions of Protonix and Ticagrelor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Vomiting

40-49:

  1. Herpes simplex (herpes simplex is a common viral infection)
  2. Hyperacusis (disorder in loudness perception)
  3. Hyperplasia (enlargement of an organ or tissue)
  4. Hypertension (high blood pressure)
  5. Influenza like illness
  6. Injection site pain
  7. Insomnia (sleeplessness)
  8. Iron deficiency
  9. Menstrual disorder (disease of menstrual cycle)
  10. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

50-59:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)
  3. Death
  4. Dyspepsia (indigestion)
  5. Renal failure (kidney dysfunction)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Bk virus infection
  9. Hepatic failure (liver failure)
  10. Pneumonia fungal

60+:

  1. Chronic kidney disease
  2. Constipation
  3. Body temperature decreased
  4. Brain natriuretic peptide increased
  5. Cardiac failure congestive
  6. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  7. Diarrhoea
  8. Drug administration error
  9. Dysgeusia (disorder of the sense of taste)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 13 people, 37.14%
  2. High Blood Pressure: 12 people, 34.29%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 20.00%
  4. Pain: 6 people, 17.14%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 17.14%
  6. Sleep Disorder: 6 people, 17.14%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 17.14%
  8. Constipation: 6 people, 17.14%
  9. Diabetes: 5 people, 14.29%
  10. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

Do you take Protonix and Ticagrelor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Protonix and Ticagrelor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ticagrelor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Protonix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ticagrelor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium and ticagrelor (the active ingredients of Protonix and Ticagrelor, respectively), and Protonix and Ticagrelor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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