Protonix and Ubrelvy drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Ubrelvy (ubrogepant). Common drug interactions include arthralgia among females and gallbladder disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Protonix and Ubrelvy. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
What is Ubrelvy?
Ubrelvy has active ingredients of ubrogepant. eHealthMe is studying from 3,585 Ubrelvy users. Check the latest studies of Ubrelvy.
34 people who take Protonix and Ubrelvy together, and have interactions are studied.

What are the common drug interactions of Protonix and Ubrelvy, by gender? *:
female:
- Arthralgia (joint pain)
- Migraine (headache)
- Rash
- Chest pain
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Headache (pain in head)
- Hypotension (abnormally low blood pressure)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Infusion related reaction
male:
- Gallbladder disorder
- Drug ineffective
- Hypertension (high blood pressure)
- Irritability
- Migraine (headache)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
What are the common drug interactions of Protonix and Ubrelvy, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dental caries
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Tooth erosion (dissolving teeth)
- Tooth loss
30-39:
- Rash
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Pain
- Pruritus (severe itching of the skin)
- White blood cell count decreased
40-49:
- Abdominal pain upper
- Bone pain
- Chest discomfort
- Diarrhoea
- Dry mouth
- Dyspepsia (indigestion)
- Dyspnoea (difficult or laboured respiration)
- Injection site pain
- Migraine (headache)
- Nausea (feeling of having an urge to vomit)
50-59:
- Adverse drug reaction
- Asthma
- Cough
- Dyspnoea (difficult or laboured respiration)
- Hypertension (high blood pressure)
60+:
- Drug ineffective
- Aphasia (damage to the parts of the brain that control language)
- Nausea (feeling of having an urge to vomit)
- Urinary tract infection
- Vomiting
- Aura
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Pneumonia
- Back pain
What are the existing conditions these people have? *
- Migraine (headache): 15 people, 44.12%
- Immunodeficiency Common Variable: 7 people, 20.59%
- Pain: 5 people, 14.71%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 11.76%
- Asthma: 4 people, 11.76%
- Nausea (feeling of having an urge to vomit): 3 people, 8.82%
- Stress And Anxiety: 2 people, 5.88%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.88%
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.88%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Protonix and Ubrelvy?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Protonix and Ubrelvy:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ubrelvy:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ubrelvy and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pantoprazole sodium and ubrogepant (the active ingredients of Protonix and Ubrelvy, respectively), and Protonix and Ubrelvy (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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