Protopic and Allegra allergy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protopic (tacrolimus) and Allegra allergy (fexofenadine hydrochloride). Common drug interactions include depression among females and injection site pain among males.

The phase IV clinical study analyzes what interactions people have when they take Protopic and Allegra allergy. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

What is Allegra allergy?

Allegra allergy has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 13,594 Allegra allergy users. Check the latest studies of Allegra allergy.

On Jul, 29, 2026

24 people who take Protopic and Allegra allergy together, and have interactions are studied.

Protopic and Allegra allergy drug interactions.

What are the common drug interactions of Protopic and Allegra Allergy, by gender? *:

female:

Depression
Fungal infection
Hypotension (abnormally low blood pressure)
Oral candidiasis (fungal infection of mouth)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Weight decreased
Dry mouth
Immunodeficiency
Pruritus (severe itching of the skin)
Rash

male:

Injection site pain
Injection site swelling
Back disorder
Blood testosterone decreased
Diarrhoea
Hypothalamo-pituitary disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Protopic and Allegra Allergy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Discomfort
Drug ineffective
Rash
Sleep disorder

20-29:

n/a

30-39:

Rash
Abortion spontaneous (naturally occurring miscarriage)
Back disorder
Blood testosterone decreased
Hypothalamo-pituitary disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)

40-49:

Fungal infection
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Immunodeficiency common variable
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Nausea (feeling of having an urge to vomit)
Oral candidiasis (fungal infection of mouth)
Pruritus (severe itching of the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Weight decreased

50-59:

Injection site pain
Injection site swelling

60+:

n/a

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 14 people, 58.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 29.17%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 29.17%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 16.67%
Allergic Rhinitis: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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