Protopic and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protopic (tacrolimus) and Ms contin (morphine sulfate). Common drug interactions include arthralgia among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Protopic and Ms contin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

On Jul, 10, 2026

13 people who take Protopic and Ms contin together, and have interactions are studied.

Protopic and Ms contin drug interactions.

What are the common drug interactions of Protopic and Ms Contin, by gender? *:

female:

Arthralgia (joint pain)
Rash
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood sodium decreased
Depression
Joint swelling
Pneumonia
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Therapeutic response decreased (less preventive response)
Thirst

male:

Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Candidiasis (candidiasis or thrush is a fungal infection)
Cellulitis (infection under the skin)
Confusional state
Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Fibrous histiocytoma (non cancer fibrous skin lesion)
Haematological malignancy (cancer that affect blood, bone marrow, and lymph nodes)

What are the common drug interactions of Protopic and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arthralgia (joint pain)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood sodium decreased
Joint swelling
Pneumonia
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Rash
Therapeutic response decreased (less preventive response)
Thirst
Weight decreased

60+:

Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Candidiasis (candidiasis or thrush is a fungal infection)
Cellulitis (infection under the skin)
Confusional state
Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Fibrous histiocytoma (non cancer fibrous skin lesion)
Haematological malignancy (cancer that affect blood, bone marrow, and lymph nodes)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 38.46%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 5 people, 38.46%
Menopausal Symptoms: 5 people, 38.46%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 5 people, 38.46%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 15.38%
Hiv Infection: 2 people, 15.38%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 15.38%
Renal Cell Carcinoma (a kidney cancer): 1 person, 7.69%
Depression: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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