Provera and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Aricept (donepezil hydrochloride). Common drug interactions include electrocardiogram qt prolonged among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Provera and Aricept. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

On Jul, 08, 2026

44 people who take Provera and Aricept together, and have interactions are studied.

What are the common drug interactions of Provera and Aricept, by gender? *:

female:

Electrocardiogram qt prolonged
Sedation
Speech disorder
Depressed level of consciousness
Depression
Asthenia (weakness)
Lethargy (tiredness)
Abdominal pain upper
Acute hepatic failure
Autoimmune hepatitis

male:

Fall
Asthenia (weakness)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Application site erythema (redness of the skin at application site)
Application site reaction
Blood glucose increased
Blood urea increased
Lymphocyte count decreased
Lymphocyte percentage decreased
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

What are the common drug interactions of Provera and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Productive cough

40-49:

Asthenia (weakness)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Fall
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Unresponsive to stimuli
Electrocardiogram st segment elevation

50-59:

Electrocardiogram qt prolonged
Acute hepatic failure
Autoimmune hepatitis
Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Asthenia (weakness)
Atrioventricular dissociation (av block)
Confusional state
Cough
Diarrhoea

60+:

Speech disorder
Depressed level of consciousness
Anaemia (lack of blood)
Application site erythema (redness of the skin at application site)
Application site reaction
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Breast cancer female
Colon cancer
Confusion

What are the existing conditions these people have? *

Sleep Disorder: 15 people, 34.09%
Constipation: 15 people, 34.09%
Depression: 11 people, 25.00%
Stress And Anxiety: 9 people, 20.45%
Fever: 8 people, 18.18%
Pain: 8 people, 18.18%
Nausea (feeling of having an urge to vomit): 8 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 18.18%
Lymphangioleiomyomatosis (a rare lung condition that affects a certain type of muscle cell and only occurs in women): 7 people, 15.91%
Dementia (madness): 7 people, 15.91%

* Approximation only. Some reports may have incomplete information.

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