Provera and Betaseron drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Betaseron (interferon beta-1b). Common drug interactions include migraine among females and breast cancer female among males.
The phase IV clinical study analyzes what interactions people have when they take Provera and Betaseron. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Provera?
Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.
What is Betaseron?
Betaseron has active ingredients of interferon beta-1b. It is often used in multiple sclerosis. eHealthMe is studying from 26,886 Betaseron users. Check the latest studies of Betaseron.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
45 people who take Provera and Betaseron together, and have interactions are studied.

What are the common drug interactions of Provera and Betaseron, by gender? *:
female:
- Migraine (headache)
- Uterine haemorrhage (uterine bleeding)
- Nausea (feeling of having an urge to vomit)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Dyspnoea (difficult or laboured respiration)
- Hyperthyroidism (over activity of the thyroid gland)
- Injection site reaction
- Pain in extremity
- Speech disorder
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
male:
- Breast cancer female
- Drug ineffective
What are the common drug interactions of Provera and Betaseron, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pyrexia (fever)
30-39:
- Hyperthyroidism (over activity of the thyroid gland)
- Nausea (feeling of having an urge to vomit)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Dizziness
- Hyperhidrosis (abnormally increased sweating)
- Increased appetite
- Pain in extremity
- Pallor
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Retching (strong involuntary effort to vomit)
40-49:
- Abdominal pain
- Fatigue (feeling of tiredness)
- Abdominal distension
- Device dislocation
- Dysmenorrhoea (painful menstruation)
- Lymphocyte count decreased
- Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
- Migraine (headache)
- Uterine haemorrhage (uterine bleeding)
- Contusion (a type of hematoma of tissue in which capillaries)
50-59:
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Coronary artery spasm
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fatigue (feeling of tiredness)
- Heart rate increased
- Hepatic failure (liver failure)
- Oesophageal disorder (disease of oesophagus)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pancreatic carcinoma (pancreatic cancer)
60+:
- Breast cancer female
- Lymphoma (cancer that begins in immune system cells)
- Injection site erythema (redness at injection site)
- Injection site mass
- Injection site pain
- Injection site reaction
- Lung infection
- Lung neoplasm (tumour of lung)
- Lung neoplasm malignant (cancer tumour of lung)
- Metastases to lymph nodes (cancer spreads to lymph node)
What are the existing conditions these people have? *
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 7 people, 15.56%
- Pain: 3 people, 6.67%
- Migraine Without Aura (headache without neurological problems): 3 people, 6.67%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 6.67%
- Depression: 3 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Provera and Betaseron?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Provera and Betaseron:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Betaseron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Provera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Betaseron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on medroxyprogesterone acetate and interferon beta-1b (the active ingredients of Provera and Betaseron, respectively), and Provera and Betaseron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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