Provera and Emla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Emla (lidocaine; prilocaine). Common drug interactions include migraine among females.

The phase IV clinical study analyzes what interactions people have when they take Provera and Emla. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

On Jul, 30, 2026

24 people who take Provera and Emla together, and have interactions are studied.

What are the common drug interactions of Provera and Emla, by gender? *:

female:

Migraine (headache)
Alopecia (absence of hair from areas of the body)
Influenza
Intervertebral disc protrusion (spinal disc protrusion)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphoedema (localized fluid retention and tissue swelling)
Mucosal inflammation (infection of mucous membrane)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Pain in jaw
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)

male:

n/a

What are the common drug interactions of Provera and Emla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Colitis (inflammation of colon)
Atrial thrombosis (blood clot that develops in an artery)
Endocarditis (inflammation in heart muscle)
Fear
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary infarction (death of a small area of lung)

20-29:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pruritus (severe itching of the skin)
Rash
Upper respiratory tract infection
Myocarditis (inflammation of heart muscle myocardium)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Cardiac failure
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

30-39:

Abdominal pain upper
Activities of daily living impaired
Anger
Anxiety
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Balance disorder
Chromatopsia (visual defect in which colourless objects appear to be tinged with colour)
Communication disorder (speech and language disorder)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)

40-49:

Dysphagia (a condition in which swallowing is difficult or painful)
General physical health deterioration (weak health status)
Influenza
Intervertebral disc protrusion (spinal disc protrusion)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphoedema (localized fluid retention and tissue swelling)
Migraine (headache)
Mucosal inflammation (infection of mucous membrane)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Pain in jaw

50-59:

n/a

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Ejection fraction decreased (systolic heart failure)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 41.67%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 10 people, 41.67%
Stress And Anxiety: 8 people, 33.33%
Pain: 8 people, 33.33%
Nausea And Vomiting: 7 people, 29.17%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 20.83%
Multiple Myeloma (cancer of the plasma cells): 5 people, 20.83%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 20.83%
Blood Pressure Abnormal: 3 people, 12.50%
Dehydration (dryness resulting from the removal of water): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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