Provera and Epivir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Epivir (lamivudine). Common drug interactions include anaemia among females and inflammation among males.
The phase IV clinical study analyzes what interactions people have when they take Provera and Epivir. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Provera?
Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.
What is Epivir?
Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.
12 people who take Provera and Epivir together, and have interactions are studied.

What are the common drug interactions of Provera and Epivir, by gender? *:
female:
- Anaemia (lack of blood)
- Blood creatinine increased
- Blood urea decreased
- Bone density decreased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Gait disturbance
- Lactic acidosis (low ph in body tissues)
- Multi-organ failure (multisystem organ failure)
- Neuropathy peripheral (surface nerve damage)
- Abasia (inability to walk)
male:
- Inflammation
- Osteonecrosis (death of bone)
- Pain
- Synovial disorder (disease of synovial joint)
What are the common drug interactions of Provera and Epivir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abortion spontaneous (naturally occurring miscarriage)
- Complications of maternal exposure to therapeutic drugs
- Inflammation
- Osteonecrosis (death of bone)
- Pain
- Pelvic inflammatory disease
- Synovial disorder (disease of synovial joint)
30-39:
- Anaemia (lack of blood)
- Blood creatinine increased
- Blood urea decreased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Lactic acidosis (low ph in body tissues)
- Multi-organ failure (multisystem organ failure)
- Neuropathy peripheral (surface nerve damage)
- Abasia (inability to walk)
- Abdominal pain
- Blood albumin decreased
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Bone density decreased
- Gait disturbance
- Fall
- Loss of consciousness
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Hiv Infection: 6 people, 50.00%
- Hepatic Neoplasm Malignant (liver cancer): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Provera and Epivir?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Provera and Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Provera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on medroxyprogesterone acetate and lamivudine (the active ingredients of Provera and Epivir, respectively), and Provera and Epivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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