Provera and Migranal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Migranal (dihydroergotamine mesylate). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Provera and Migranal. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Migranal?

Migranal has active ingredients of dihydroergotamine mesylate. It is often used in migraine. eHealthMe is studying from 560 Migranal users. Check the latest studies of Migranal.



On Jul, 13, 2026

29 people who take Provera and Migranal together, and have interactions are studied.

Provera and Migranal drug interactions.

What are the common drug interactions of Provera and Migranal, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Hypersensitivity
  4. Infection
  5. Influenza like illness
  6. Infusion site pain
  7. Nephrolithiasis (calculi in the kidneys)
  8. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  9. Asthma
  10. Epistaxis (bleed from the nose)

male:

n/a

What are the common drug interactions of Provera and Migranal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Osteopenia (a condition where bone mineral density is lower than normal)
  2. Osteoporosis (bones weak and more likely to break)
  3. Patella fracture
  4. Adjustment disorder
  5. Brain neoplasm (tumour of brain)
  6. Candidiasis (candidiasis or thrush is a fungal infection)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Constipation
  9. Dependent personality disorder
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Nephrolithiasis (calculi in the kidneys)
  4. Epistaxis (bleed from the nose)
  5. Paranasal cyst (cyst near the nose)
  6. Asthma
  7. Back pain
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Diarrhoea
  10. Dizziness

50-59:

  1. Body mass index increased
  2. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  3. Cystic fibrosis (disease of the secretary glands)
  4. Immunisation reaction
  5. Difficulty in walking
  6. Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
  7. Oedema lower limb (fluid collection in tissue of lower leg)
  8. Pain in limb
  9. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
  10. Fatigue (feeling of tiredness)

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 55.17%
  2. Headache (pain in head): 6 people, 20.69%
  3. Pain: 5 people, 17.24%
  4. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 13.79%
  5. Rashes (redness): 4 people, 13.79%
  6. Primary Immunodeficiency Syndrome: 4 people, 13.79%
  7. Neck Pain: 4 people, 13.79%
  8. Nausea And Vomiting: 4 people, 13.79%
  9. Nausea (feeling of having an urge to vomit): 4 people, 13.79%
  10. Itching: 4 people, 13.79%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Provera and Migranal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Provera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Migranal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Provera and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Migranal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate and dihydroergotamine mesylate (the active ingredients of Provera and Migranal, respectively), and Provera and Migranal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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