Provera and Plan b drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Plan b (levonorgestrel). Common drug interactions include menstruation irregular among females.

The phase IV clinical study analyzes what interactions people have when they take Provera and Plan b. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Plan b?

Plan b has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 38,623 Plan b users. Check the latest studies of Plan b.

On Aug, 09, 2026

71 people who take Provera and Plan b together, and have interactions are studied.

What are the common drug interactions of Provera and Plan B, by gender? *:

female:

Menstruation irregular
Breast cancer female
Vomiting
Vaginal discharge
Hot flush (sudden feelings of heat)
Metrorrhagia (uterine bleeding at irregular intervals)
Drug ineffective
Insomnia (sleeplessness)
Pelvic pain
Fatigue (feeling of tiredness)

male:

n/a

What are the common drug interactions of Provera and Plan B, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective
Menstruation delayed (late menstruation cycle)
Menstruation irregular
Dysmenorrhoea (painful menstruation)
Abdominal pain
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Maternal exposure during pregnancy (use of substance during pregnancy)
Mood altered (changes in mood)
Stress
Vaginal discharge

20-29:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Femoral neck fracture (neck of femur bone fracture)
Abdominal pain
Dizziness
Dysmenorrhoea (painful menstruation)
Headache (pain in head)
Vaginal haemorrhage (vaginal bleeding)
Breast cancer female
Hot flush (sudden feelings of heat)

30-39:

Abdominal pain lower
Nipple pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Abdominal pain upper
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Headache (pain in head)
Menstruation irregular
Metrorrhagia (uterine bleeding at irregular intervals)
Nausea (feeling of having an urge to vomit)
Pelvic pain

40-49:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Brain neoplasm (tumour of brain)
Headache (pain in head)
Hydrocephalus (water on the brain)
Meningioma (a diverse set of tumours arising from the meninges)
Menstruation delayed (late menstruation cycle)
Muscular weakness (muscle weakness)
Neck pain
Nervous system disorder (a general class of medical conditions affecting the nervous system)

50-59:

n/a

60+:

n/a

* Approximation only. Some reports may have incomplete information.

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