Provera and Theo-dur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Theo-dur (theophylline). Common drug interactions include blood cholesterol increased among females and abdominal adhesions among males.

The phase IV clinical study analyzes what interactions people have when they take Provera and Theo-dur. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Theo-dur?

Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.



On Jul, 30, 2026

25 people who take Provera and Theo-dur together, and have interactions are studied.

Provera and Theo-dur drug interactions.

What are the common drug interactions of Provera and Theo-Dur, by gender? *:

female:

  1. Blood cholesterol increased
  2. Chronic respiratory failure
  3. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  4. Muscular weakness (muscle weakness)
  5. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  6. Nausea (feeling of having an urge to vomit)
  7. Vomiting
  8. Breast cancer
  9. Cellulitis (infection under the skin)
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Abdominal adhesions (inflammation of abdomen)
  2. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  3. Autonomic failure syndrome (a degenerative disease of the autonomic nervous system)
  4. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  5. Blood glucose fluctuation
  6. Cardiolipin antibody positive
  7. Cerebellar ataxia (loss of coordination)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Constipation
  10. Decreased appetite

What are the common drug interactions of Provera and Theo-Dur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abnormal behaviour
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Arthralgia (joint pain)
  4. Bipolar disorder (mood disorder)
  5. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  6. Cough
  7. Depression
  8. Drug maladministration
  9. Fall
  10. Hallucination (an experience involving the perception of something not present)

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Blood potassium decreased
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Haematocrit decreased
  5. Haemoglobin decreased
  6. Influenza like illness
  7. Vomiting
  8. Weight decreased
  9. Blood pressure decreased
  10. Cellulitis (infection under the skin)

50-59:

  1. Hyperlipidaemia (presence of excess lipids in the blood)
  2. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
  3. Hypertension (high blood pressure)
  4. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  5. Hypophagia (reduced food intake)
  6. Hypoxia (low oxygen in tissues)
  7. Injury
  8. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  9. Nephrosclerosis (hardening of the kidney due to renovascular disease)
  10. Renal failure acute (rapid kidney dysfunction)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Nausea (feeling of having an urge to vomit)
  3. Arrhythmia (irregular heartbeat)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Asthenia (weakness)
  6. Atrial tachycardia (rhythm disturbance that arises in the atria)
  7. Attention deficit/hyperactivity disorder
  8. Autonomic failure syndrome (a degenerative disease of the autonomic nervous system)
  9. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  10. Blood amylase increased

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 8 people, 32.00%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 8 people, 32.00%
  3. Impaired Gastric Emptying: 2 people, 8.00%
  4. High Blood Cholesterol: 2 people, 8.00%
  5. Dyspnea (difficult or laboured breathing): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Provera and Theo-dur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Provera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Theo-dur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Provera and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Theo-dur and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate and theophylline (the active ingredients of Provera and Theo-dur, respectively), and Provera and Theo-dur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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