Provera and Velcade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Velcade (bortezomib). Common drug interactions include influenza like illness among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Provera and Velcade. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Velcade?

Velcade has active ingredients of bortezomib. It is often used in multiple myeloma. eHealthMe is studying from 66,422 Velcade users. Check the latest studies of Velcade.

On Jul, 13, 2026

36 people who take Provera and Velcade together, and have interactions are studied.

What are the common drug interactions of Provera and Velcade, by gender? *:

female:

Influenza like illness
Spinal pain (pain in spine)
Crepitations (noises are produced by the rubbing of parts one against the other)
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Myocarditis (inflammation of heart muscle myocardium)
Oedema (fluid collection in tissue)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)

male:

Anxiety
Death
Oedema peripheral (superficial swelling)
Pain
Pain in extremity
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Rash
Rash papular (redness with papule)
Scar
Sclerodactylia (disabling trophic changes and deformities of the hands and fingers)

What are the common drug interactions of Provera and Velcade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Myocarditis (inflammation of heart muscle myocardium)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Cardiac failure
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pruritus (severe itching of the skin)
Rash
Upper respiratory tract infection

30-39:

Scar
Cyst (a closed sac)
Deformity (disfigurement)
Device related infection
Diarrhoea
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Muscle tightness
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

40-49:

Emotional distress
Infection
Intervertebral disc protrusion (spinal disc protrusion)
Mucosal inflammation (infection of mucous membrane)
Neuropathy peripheral (surface nerve damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Spinal osteoarthritis (joint cartilage loss in spine)

50-59:

Bence jones proteinuria (immunoglobulin light chain found in the urine)
Benign breast neoplasm (benign (non-cancerous) tumours of the breast)
Bone loss
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deformity (disfigurement)
Diarrhoea
Disability
Dyspnoea (difficult or laboured respiration)
Ear pain

60+:

Headache (pain in head)
Influenza
Injection site erythema (redness at injection site)
Injection site swelling
Pyrexia (fever)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 6 people, 16.67%
Stress And Anxiety: 4 people, 11.11%
Nausea And Vomiting: 4 people, 11.11%
Bone Neoplasm Malignant (cancer of bone): 3 people, 8.33%
Pain: 2 people, 5.56%
Immunodeficiency Disorders: 2 people, 5.56%
Chest Pain: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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