Provigil and Sodium fluoride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provigil (modafinil) and Sodium fluoride (fluoride). Common drug interactions include atrial fibrillation among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Provigil and Sodium fluoride. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Provigil?

Provigil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 25,230 Provigil users. Check the latest studies of Provigil.

What is Sodium fluoride?

Sodium fluoride has active ingredients of fluoride. It is often used in dental cavities. eHealthMe is studying from 1,216 Sodium fluoride users. Check the latest studies of Sodium fluoride.

On Aug, 04, 2026

14 people who take Provigil and Sodium fluoride together, and have interactions are studied.

Provigil and Sodium fluoride drug interactions.

What are the common drug interactions of Provigil and Sodium Fluoride, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Therapeutic response unexpected
Activities of daily living impaired
Impaired driving ability
Pain
Spinal disorder (disease of spine a back bone)

male:

Abdominal discomfort
Blindness
Systolic dysfunction (impaired ventricular contraction)
Oedema peripheral (superficial swelling)
Apathy
Asthenia (weakness)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Attention deficit/hyperactivity disorder
Balance disorder
Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Provigil and Sodium Fluoride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Activities of daily living impaired
Impaired driving ability
Pain
Spinal disorder (disease of spine a back bone)

60+:

Blindness
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Balance disorder
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Corneal disorder
Dental caries
Depression
Dizziness

What are the existing conditions these people have? *

Drowsiness: 7 people, 50.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 28.57%
Pain: 3 people, 21.43%
Muscle Spasms (muscle contraction): 3 people, 21.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 21.43%
Affective Disorder (mental disorder): 2 people, 14.29%
Depression: 2 people, 14.29%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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