Prozac and Desogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Desogen (desogestrel; ethinyl estradiol). Common drug interactions include abdominal pain among females.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Desogen. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Desogen?

Desogen has active ingredients of desogestrel; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 664 Desogen users. Check the latest studies of Desogen.



On Aug, 01, 2026

13 people who take Prozac and Desogen together, and have interactions are studied.

Prozac and Desogen drug interactions.

What are the common drug interactions of Prozac and Desogen, by gender? *:

female:

  1. Abdominal pain
  2. Back pain
  3. Dysarthria (speech disorder)
  4. Dyspnoea (difficult or laboured respiration)
  5. Escherichia test positive
  6. Fibromyalgia syndrome (constant pain in their muscles and soft tissues)
  7. Increased activity
  8. Monoparesis (one limb is very weak, but not completely paralyzed)
  9. Myoclonic jerks (involuntary twitching of a muscle or group of muscles)
  10. Overdose

male:

n/a

What are the common drug interactions of Prozac and Desogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cholecystitis (infection of gallbladder)
  2. Dyspnoea (difficult or laboured respiration)
  3. Pain
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Vomiting
  6. Vomiting psychogenic

30-39:

  1. Dysarthria (speech disorder)
  2. Fibromyalgia syndrome (constant pain in their muscles and soft tissues)
  3. Monoparesis (one limb is very weak, but not completely paralyzed)
  4. Overdose
  5. Post-traumatic stress disorder
  6. Renal failure (kidney dysfunction)
  7. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  8. Suicidal ideation
  9. Weight increased
  10. Abdominal pain

40-49:

  1. Chest pain
  2. Increased activity
  3. Pulmonary embolism (blockage of the main artery of the lung)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  2. Premenstrual Syndrome: 1 person, 7.69%
  3. Pain: 1 person, 7.69%
  4. Indigestion: 1 person, 7.69%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
  6. High Blood Cholesterol: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prozac and Desogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Desogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Desogen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and desogestrel; ethinyl estradiol (the active ingredients of Prozac and Desogen, respectively), and Prozac and Desogen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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