Prozac and Dexlansoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Dexlansoprazole (dexlansoprazole). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Dexlansoprazole. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Dexlansoprazole?

Dexlansoprazole has active ingredients of dexlansoprazole. eHealthMe is studying from 3,192 Dexlansoprazole users. Check the latest studies of Dexlansoprazole.



On Jul, 27, 2026

23 people who take Prozac and Dexlansoprazole together, and have interactions are studied.

Prozac and Dexlansoprazole drug interactions.

What are the common drug interactions of Prozac and Dexlansoprazole, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Dysphonia (speech disorder attributable to a disorder of phonation)
  5. Fatigue (feeling of tiredness)
  6. Gait disturbance
  7. Irritability
  8. Muscle spasms (muscle contraction)
  9. Muscle tightness
  10. Throat tightness

male:

  1. Chronic kidney disease
  2. Renal haemangioma (kidney tumour filled with blood)
  3. Sluggishness (lacking alertness)
  4. Urinary retention (the inability to completely or partially empty the bladder)
  5. Urinary tract infection
  6. Vitamin d decreased
  7. Activities of daily living impaired
  8. Completed suicide (act of taking one's own life)
  9. Dysarthria (speech disorder)
  10. General physical health deterioration (weak health status)

What are the common drug interactions of Prozac and Dexlansoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Completed suicide (act of taking one's own life)
  2. Death

40-49:

  1. Diarrhoea
  2. Feeling hot
  3. Nausea (feeling of having an urge to vomit)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Gait disturbance
  3. Irritability
  4. Muscle tightness
  5. Throat tightness
  6. Chronic kidney disease
  7. Dysgeusia (disorder of the sense of taste)
  8. Renal failure (kidney dysfunction)
  9. Renal injury (kidney injury)
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

60+:

  1. Chronic kidney disease
  2. Dysarthria (speech disorder)
  3. Dysuria (painful or difficult urination)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Irritability
  7. Muscle spasms (muscle contraction)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Sluggishness (lacking alertness)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 39.13%
  2. Stress And Anxiety: 6 people, 26.09%
  3. Pain: 5 people, 21.74%
  4. Hypersensitivity: 3 people, 13.04%
  5. High Blood Pressure: 3 people, 13.04%
  6. Sleep Disorder: 3 people, 13.04%
  7. Blood Potassium Decreased: 2 people, 8.70%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.70%
  9. Hyperglycemia (high blood sugar): 2 people, 8.70%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prozac and Dexlansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dexlansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexlansoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and dexlansoprazole (the active ingredients of Prozac and Dexlansoprazole, respectively), and Prozac and Dexlansoprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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