Prozac and Diamox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Diamox (acetazolamide). Common drug interactions include haemorrhage among females and rash among males.
The phase IV clinical study analyzes what interactions people have when they take Prozac and Diamox. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.
What is Prozac?
Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.
What is Diamox?
Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.
79 people who take Prozac and Diamox together, and have interactions are studied.

What are the common drug interactions of Prozac and Diamox, by gender? *:
female:
- Haemorrhage (bleeding)
- Hyperaemia (increase of blood flow to different tissues in the body)
- Iatrogenic injury (iatrogenic injury is a form of medical error)
- Injection site infection
- Injection site mass
- Mitral valve prolapse (heart's mitral valve doesn't work well)
- Oedema peripheral (superficial swelling)
- Petechiae (a small red or purple spot caused by bleeding into the skin)
- Pulmonary oedema (fluid accumulation in the lungs)
- Pyelonephritis (inflammation of kidney caused by bacteria)
male:
- Rash
- Abasia (inability to walk)
- Abscess (pus)
- Back pain
- Bladder cancer
- Cellulitis (infection under the skin)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Eye pain
- Facial pain
- Haematuria (presence of blood in urine)
What are the common drug interactions of Prozac and Diamox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Hypersomnia (excessive daytime sleepiness (eds))
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Abdominal discomfort
- Diarrhoea
- Nausea (feeling of having an urge to vomit)
- Adverse drug reaction
- Hypophagia (reduced food intake)
20-29:
- Vomiting
- Cough
- Depressed level of consciousness
- Influenza
- Retching (strong involuntary effort to vomit)
- Pyrexia (fever)
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Crying
- Drug hypersensitivity
- Hypertension (high blood pressure)
30-39:
- Dyspnoea (difficult or laboured respiration)
- Asthenia (weakness)
- Confusion
- Fatigue (feeling of tiredness)
- Infection
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
- Nasopharyngitis (inflammation of the nasopharynx)
- Overdose
- Aortic valve replacement
40-49:
- Migraine (headache)
- Headache (pain in head)
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Abdominal distension
- Chronic kidney disease
- Death
- Haemorrhage (bleeding)
- Suicidal ideation
- Urinary tract infection
50-59:
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Abasia (inability to walk)
- Dry mouth
- Fungal infection
- Insomnia (sleeplessness)
- Ludwig angina (a type of cellulitis that involves the floor of the mouth, under the tongue)
- Osteomyelitis (infection of bone)
- Rash
- Streptococcal infection
60+:
- Anaemia (lack of blood)
- Cardiac failure congestive
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bladder cancer
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Conjunctivitis bacterial (infection of conjunctiva by bacteria)
- Constipation
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 24 people, 30.38%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 20.25%
- Pain: 15 people, 18.99%
- Stress And Anxiety: 13 people, 16.46%
- Migraine (headache): 10 people, 12.66%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 12.66%
- Insomnia (sleeplessness): 8 people, 10.13%
- Asthma: 6 people, 7.59%
- Oedema (fluid collection in tissue): 6 people, 7.59%
- Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 5 people, 6.33%
* Approximation only. Some reports may have incomplete information.
Do you take Prozac and Diamox?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Prozac and Diamox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prozac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diamox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prozac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diamox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on fluoxetine hydrochloride and acetazolamide (the active ingredients of Prozac and Diamox, respectively), and Prozac and Diamox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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