Prozac and Etoposide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Etoposide (etoposide). Common drug interactions include oxygen saturation decreased among females and encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Etoposide. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Etoposide?

Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

42 people who take Prozac and Etoposide together, and have interactions are studied.

What are the common drug interactions of Prozac and Etoposide, by gender? *:

female:

Oxygen saturation decreased
Pain
Pelvic mass
Pelvic pain
Performance status decreased
Pericardial effusion (fluid around the heart)
Productive cough
Pulmonary congestion (congestion in the lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary oedema (fluid accumulation in the lungs)

male:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Herpes virus infection
Amyotrophy (muscular wasting or atrophy)
Asthenia (weakness)
Blood culture positive
Blood ph increased
Blood potassium decreased
Blood pressure increased
Chills (felling of cold)
Colitis (inflammation of colon)

What are the common drug interactions of Prozac and Etoposide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Disease progression
Drug ineffective
Drug intolerance (drug sensitivity)
Fatigue (feeling of tiredness)

20-29:

Oxygen saturation decreased
Pelvic mass
Pelvic pain
Platelet count decreased
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Retinal haemorrhage (bleeding from retina)
Thrombocytopenia (decrease of platelets in blood)
Thromboembolism (obstruction of artery by blood clot)
Adult respiratory distress syndrome (type of lung (pulmonary) failure)

30-39:

Small intestinal obstruction (blockage in small intestine)
Pleural effusion (water on the lungs)
Productive cough
Respiratory distress (difficulty in breathing)

40-49:

Subdural haematoma (blood collects between the skull and the surface of the brain)
Thrombocytopenia (decrease of platelets in blood)

50-59:

Pneumonia
Abdominal pain
C-reactive protein increased
Gastritis (inflammation of stomach)
Neutropenia (an abnormally low number of neutrophils)
Hypoxia (low oxygen in tissues)
Pleural effusion (water on the lungs)
Cardiac disorder
Cardiomegaly (increased size of heart than normal)
Colitis (inflammation of colon)

60+:

Febrile neutropenia (fever with reduced white blood cells)
White blood cell count decreased
Herpes virus infection
Respiratory failure (inadequate gas exchange by the respiratory system)
Atelectasis (partial or complete collapse of the lung)
Blood culture positive
Chest pain
Dehydration (dryness resulting from the removal of water)
Empyema (collection of pus in a cavity in the body)
Haemoglobin decreased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 19.05%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 14.29%
Diarrhea: 6 people, 14.29%
Nausea And Vomiting: 5 people, 11.90%
Insomnia (sleeplessness): 4 people, 9.52%
Breast Cancer Metastatic: 4 people, 9.52%
Stress And Anxiety: 3 people, 7.14%
Nausea (feeling of having an urge to vomit): 3 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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