Prozac and Levofloxacin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Levofloxacin (levofloxacin; sodium chloride). Common drug interactions include dysphagia among females and syncope among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Levofloxacin. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Levofloxacin?

Levofloxacin has active ingredients of levofloxacin; sodium chloride. It is often used in sinusitis. eHealthMe is studying from 16,335 Levofloxacin users. Check the latest studies of Levofloxacin.



On Jul, 15, 2026

65 people who take Prozac and Levofloxacin together, and have interactions are studied.

Prozac and Levofloxacin drug interactions.

What are the common drug interactions of Prozac and Levofloxacin, by gender? *:

female:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Ear pain
  3. Pain
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  8. Spinal osteoarthritis (joint cartilage loss in spine)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Fall

male:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Renal failure chronic (long lasting kidney dysfunction)
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Arthropathy
  7. Atelectasis (partial or complete collapse of the lung)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Attention deficit/hyperactivity disorder
  10. Back pain

What are the common drug interactions of Prozac and Levofloxacin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Atrial thrombosis (blood clot that develops in an artery)
  2. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Injury
  5. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  6. Nystagmus (a condition of involuntary eye movement)
  7. Overdose
  8. Pain
  9. Sedation
  10. Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)

30-39:

  1. Abdominal distension
  2. Anaemia (lack of blood)
  3. Coagulopathy (blood's ability to clot is impaired)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Dyspnoea (difficult or laboured respiration)
  6. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  7. Hepatic failure (liver failure)
  8. Hypotension (abnormally low blood pressure)
  9. Leukocytosis (increased white blood cells)
  10. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

40-49:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Postmenopausal haemorrhage (post-menopausal bleeding)
  3. Renal failure acute (rapid kidney dysfunction)
  4. Renal failure chronic (long lasting kidney dysfunction)
  5. Abdominal pain
  6. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  7. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  8. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  9. Arthralgia (joint pain)
  10. Asthma

50-59:

  1. Benign ovarian tumour
  2. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  3. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  4. Chest pain
  5. Cholesteatoma (abnormal skin growth in the middle ear behind the eardrum)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Deafness neurosensory
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Dental caries
  10. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

60+:

  1. Blood lactate dehydrogenase increased
  2. Anaemia (lack of blood)
  3. Confusional state
  4. Culture urine positive
  5. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  6. Disability
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Ear pain
  9. Escherichia infection (bacterial infection by escherichia coli)
  10. Facial bones fracture (bone fracture of face)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 21 people, 32.31%
  2. High Blood Pressure: 5 people, 7.69%
  3. Stress And Anxiety: 4 people, 6.15%
  4. Headache (pain in head): 4 people, 6.15%
  5. Constipation: 4 people, 6.15%

* Approximation only. Some reports may have incomplete information.

Do you take Prozac and Levofloxacin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prozac and Levofloxacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levofloxacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levofloxacin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and levofloxacin; sodium chloride (the active ingredients of Prozac and Levofloxacin, respectively), and Prozac and Levofloxacin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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