Prozac and Mesalamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Mesalamine (mesalamine). Common drug interactions include aggression among females and neutrophil count increased among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Mesalamine. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

On Jul, 12, 2026

50 people who take Prozac and Mesalamine together, and have interactions are studied.

Prozac and Mesalamine drug interactions.

What are the common drug interactions of Prozac and Mesalamine, by gender? *:

female:

Aggression
Agitation (state of anxiety or nervous excitement)
Alcoholism (problems with alcohol)
Altered state of consciousness (altered state of mind)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety disorder
Apparent life threatening event (an acute, unexpected change in an infant's breathing behaviour that is frightening to the caretaker)
Arrhythmia (irregular heartbeat)

male:

Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
White blood cell count increased
Drug hypersensitivity
Heart rate decreased
Heart rate irregular
Weight decreased
Abdominal pain
Ankle fracture
Blood glucose decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Prozac and Mesalamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Inflammatory bowel disease
Pyelonephritis (inflammation of kidney caused by bacteria)
Clostridial infection (infectious conditions by clostridium bacteria)
Coarctation of the aorta (narrowing of the part of aorta)
Dyspepsia (indigestion)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Injection site reaction
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pruritus generalised (generalized itching)
Psoriasis (immune-mediated disease that affects the skin)

20-29:

Abdominal pain
Rectal haemorrhage (bleeding from anus)
Abortion spontaneous (naturally occurring miscarriage)
Maternal exposure during pregnancy (use of substance during pregnancy)
Vaginal haemorrhage (vaginal bleeding)

30-39:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Arthralgia (joint pain)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Pain
Vomiting
Weight decreased
Abdominal distension
Abdominal tenderness

40-49:

Mastication disorder (disease of chewing food)
Memory impairment
Mouth haemorrhage (bleeding from mouth)
Mouth injury
Multiple drug overdose accidental
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)

50-59:

Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Ear pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Seborrhoea (a disease of the sebaceous glands characterized by excessive secretion of sebum)

60+:

White blood cell count increased
Haematocrit decreased
Drug hypersensitivity
Heart rate decreased
Heart rate irregular
Alopecia (absence of hair from areas of the body)
Blood cholesterol increased
Blood pressure decreased
Dizziness
Drug ineffective

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 13 people, 26.00%
Stress And Anxiety: 9 people, 18.00%
Inflammatory Bowel Disease: 9 people, 18.00%
Diarrhea: 7 people, 14.00%
Abdominal Pain: 6 people, 12.00%
Insomnia (sleeplessness): 6 people, 12.00%
High Blood Pressure: 5 people, 10.00%
Nausea (feeling of having an urge to vomit): 5 people, 10.00%
Weakness: 4 people, 8.00%
Abdominal Pain Upper: 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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