Prozac and Minoxidil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Minoxidil (minoxidil). Common drug interactions include atelectasis among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Minoxidil. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Minoxidil?

Minoxidil has active ingredients of minoxidil. It is often used in hair loss. eHealthMe is studying from 29,925 Minoxidil users. Check the latest studies of Minoxidil.



On Jul, 19, 2026

52 people who take Prozac and Minoxidil together, and have interactions are studied.

Prozac and Minoxidil drug interactions.

What are the common drug interactions of Prozac and Minoxidil, by gender? *:

female:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
  3. Blood sodium decreased
  4. Brain stem stroke (rapid loss of brain function due to disturbance in the blood supply to the brain)
  5. Cellulitis (infection under the skin)
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Cholecystitis (infection of gallbladder)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Confusional state
  10. Delirium (wild excitement)

male:

  1. Headache (pain in head)
  2. Arthralgia (joint pain)
  3. Cardiac disorder
  4. Compression fracture (fracture due to pressure caused by injury)
  5. Confusion
  6. Pyrexia (fever)
  7. Vomiting
  8. Abdominal pain
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Bacillus infection

What are the common drug interactions of Prozac and Minoxidil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Red blood cell count decreased

20-29:

  1. Application site pruritus (application site severe itching of the skin)
  2. Application site scab (hard coating on the skin formed at application site)

30-39:

  1. Ataxia (loss of full control of bodily movements)
  2. Confusion
  3. Hallucination (an experience involving the perception of something not present)
  4. Heart rate increased
  5. Hyperglycaemia (high blood sugar)
  6. Hypertensive encephalopathy (neurological dysfunction induced by malignant hypertension)
  7. Nervousness
  8. Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
  9. Blood glucose increased
  10. Brain stem stroke (rapid loss of brain function due to disturbance in the blood supply to the brain)

40-49:

  1. Confusion
  2. Distress
  3. Duodenal ulcer
  4. Duodenitis (inflammation of the duodenum)
  5. Dyspnoea (difficult or laboured respiration)
  6. Flatulence (flatus expelled through the anus)
  7. Gastric erosions (gradual destruction of surface layer of the membrane lining the stomach)
  8. Gastric ulcer (stomach ulcer)
  9. Gout (uric acid crystals building up in the body)
  10. Heart rate irregular

50-59:

  1. Arthralgia (joint pain)
  2. Bradycardia (abnormally slow heart action)
  3. Cholecystitis (infection of gallbladder)
  4. Compression fracture (fracture due to pressure caused by injury)
  5. Confusional state
  6. Difficulty in walking
  7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  8. Drug specific antibody present
  9. Headache (pain in head)
  10. Hyperreflexia (overactive or over responsive reflexes)

60+:

  1. Hair colour changes
  2. Blood sodium increased
  3. Pyrexia (fever)
  4. Renal failure (kidney dysfunction)
  5. Weight increased
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Dyspnoea (difficult or laboured respiration)
  8. Fluid retention (an abnormal accumulation of fluid in the blood)
  9. Glossodynia (a burning or painful sensation in the tongue)
  10. Hypertrichosis (hair growth on the body in an amount considered abnormal)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 6 people, 11.54%
  2. High Blood Cholesterol: 6 people, 11.54%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 9.62%
  4. High Blood Pressure: 5 people, 9.62%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 7.69%
  6. Bipolar Disorder (mood disorder): 4 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prozac and Minoxidil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Minoxidil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Minoxidil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and minoxidil (the active ingredients of Prozac and Minoxidil, respectively), and Prozac and Minoxidil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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