Prozac and Tenuate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Tenuate (diethylpropion hydrochloride). Common drug interactions include dyspnoea among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Tenuate. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Tenuate?

Tenuate has active ingredients of diethylpropion hydrochloride. It is often used in weight loss. eHealthMe is studying from 336 Tenuate users. Check the latest studies of Tenuate.



On Jul, 15, 2026

32 people who take Prozac and Tenuate together, and have interactions are studied.

Prozac and Tenuate drug interactions.

What are the common drug interactions of Prozac and Tenuate, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Drug hypersensitivity
  3. Drug ineffective
  4. Cardiac murmur (an heart sound in valve abnormality)
  5. Fatigue (feeling of tiredness)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Asthenia (weakness)
  8. Cardiovascular disorder (heart diseases)
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Valvular heart disease (diseases of the heart valves)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Cardiovascular disorder (heart diseases)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Drug ineffective
  5. Emotional distress
  6. General physical health deterioration (weak health status)
  7. Injury
  8. Pain
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Rash

What are the common drug interactions of Prozac and Tenuate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Emotional distress
  3. General physical health deterioration (weak health status)
  4. Injury
  5. Pain
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Asthenia (weakness)
  8. Cardiovascular disorder (heart diseases)
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

40-49:

  1. Pulmonary valve incompetence
  2. Respiratory distress (difficulty in breathing)
  3. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  4. Superior vena caval obstruction (obstruction of blood flow through the superior vena cava)
  5. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  6. Tricuspid valve incompetence (inefficient heart valve)
  7. Asthma
  8. Cardiac failure
  9. Cardiac output decreased
  10. Cor pulmonale (enlargement of the right ventricle of the heart)

50-59:

  1. Cardiovascular disorder (heart diseases)
  2. Crying
  3. Asthenia (weakness)
  4. Drug ineffective
  5. Dysmenorrhoea (painful menstruation)
  6. Dyspnoea (difficult or laboured respiration)
  7. Insomnia (sleeplessness)
  8. Pain
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Synovial cyst (cyst of joint filled with synovial fluid)

60+:

n/a

What are the existing conditions these people have? *

  1. Birth Control: 3 people, 9.38%
  2. Appetite Disorder (abnormal eating habits): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Prozac and Tenuate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prozac and Tenuate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tenuate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tenuate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and diethylpropion hydrochloride (the active ingredients of Prozac and Tenuate, respectively), and Prozac and Tenuate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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