Prozac and Uloric drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Uloric (febuxostat). Common drug interactions include shock haemorrhagic among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Uloric. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

On Jul, 09, 2026

40 people who take Prozac and Uloric together, and have interactions are studied.

What are the common drug interactions of Prozac and Uloric, by gender? *:

female:

Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stomatitis (inflammation of mucous membrane of mouth)
Weight increased
Fatigue (feeling of tiredness)
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Renal failure (kidney dysfunction)
Asthenia (weakness)

male:

Chest pain
Flushing (the warm, red condition of human skin)
Blood creatinine increased
Blood pressure increased
Bowel movement irregularity
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Bruxism (habitual grinding of the teeth, typically during sleep)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Constipation

What are the common drug interactions of Prozac and Uloric, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

40-49:

Abdominal pain upper
Rash

50-59:

Agitation (state of anxiety or nervous excitement)
Aphasia (damage to the parts of the brain that control language)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dysgraphia (impaired ability to learn to write)
Flat affect (absence of emotional response to a situation)
Flushing (the warm, red condition of human skin)

60+:

Fatigue (feeling of tiredness)
Chronic kidney disease
Thrombosis (formation of a blood clot inside a blood vessel)
Septic shock (shock due to blood infection)
Chest pain
Haemorrhage (bleeding)
Nephrolithiasis (calculi in the kidneys)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Tardive dyskinesia (a disorder that involves involuntary movements)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 15.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 12.50%
High Blood Cholesterol: 5 people, 12.50%
High Blood Pressure: 4 people, 10.00%
Asthma: 3 people, 7.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 7.50%
Pain: 3 people, 7.50%
Infection: 3 people, 7.50%
Stress And Anxiety: 3 people, 7.50%
Diabetes: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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