Pulmicort flexhaler and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pulmicort flexhaler (budesonide) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include pulmonary arterial hypertension among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Pulmicort flexhaler and Bactrim. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Pulmicort flexhaler?

Pulmicort flexhaler has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 5,527 Pulmicort flexhaler users. Check the latest studies of Pulmicort flexhaler.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

24 people who take Pulmicort flexhaler and Bactrim together, and have interactions are studied.

Pulmicort flexhaler and Bactrim drug interactions.

What are the common drug interactions of Pulmicort Flexhaler and Bactrim, by gender? *:

female:

Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Rash
Road traffic accident
Swelling face
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Throat irritation
Drug ineffective
Pyrexia (fever)
Dyspnoea (difficult or laboured respiration)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal injury (kidney injury)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Abdominal discomfort
Blood creatinine increased
Compression fracture (fracture due to pressure caused by injury)
Drug ineffective
Fatigue (feeling of tiredness)
Non-cardiac chest pain

What are the common drug interactions of Pulmicort Flexhaler and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Traumatic lung injury
Abdominal discomfort

60+:

Dyspnoea (difficult or laboured respiration)
Pyrexia (fever)
Application site scar
Arthralgia (joint pain)
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chills (felling of cold)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Decreased appetite
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Pain: 5 people, 20.83%
High Blood Pressure: 5 people, 20.83%
Sinusitis (inflammation of sinus): 4 people, 16.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 12.50%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 12.50%
Multiple Allergies (allergy to multiple agents): 3 people, 12.50%
High Blood Cholesterol: 3 people, 12.50%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 12.50%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 12.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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