Purinethol and Flovent drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Purinethol (mercaptopurine) and Flovent (fluticasone propionate). Common drug interactions include abdominal pain among females and acid fast bacilli infection among males.
The phase IV clinical study analyzes what interactions people have when they take Purinethol and Flovent. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Purinethol?
Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.
What is Flovent?
Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.
12 people who take Purinethol and Flovent together, and have interactions are studied.

What are the common drug interactions of Purinethol and Flovent, by gender? *:
female:
- Abdominal pain
- Fatigue (feeling of tiredness)
- Poor venous access
- Abdominal distension
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Constipation
- Eating disorder
male:
- Acid fast bacilli infection (mycobacterium tuberculosis infection-hiv patient)
- Adverse event
- Wound infection
- Aspergillosis (an infection caused by a fungus called aspergillus)
- Bacterial infection
- Cataract (clouding of the lens inside the eye)
- Herpes simplex (herpes simplex is a common viral infection)
- Intestinal stenosis (partial obstruction that causes the centre opening of the intestine to become narrower)
- Pneumonia
- Postoperative abscess
What are the common drug interactions of Purinethol and Flovent, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Influenza
- Neutropenia (an abnormally low number of neutrophils)
- Pyrexia (fever)
- Upper respiratory tract infection
10-19:
- Abdominal distension
- Abdominal pain
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Constipation
- Eating disorder
- Fatigue (feeling of tiredness)
- Growth retardation (delayed growth)
- Ileal stenosis (obstruction in the ileal)
- Red blood cell sedimentation rate increased
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Poor venous access
- Acid fast bacilli infection (mycobacterium tuberculosis infection-hiv patient)
- Adverse event
- Aspergillosis (an infection caused by a fungus called aspergillus)
- Bacterial infection
- Cataract (clouding of the lens inside the eye)
- Herpes simplex (herpes simplex is a common viral infection)
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
- Intestinal stenosis (partial obstruction that causes the centre opening of the intestine to become narrower)
50-59:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Ataxia (loss of full control of bodily movements)
- Blood alkaline phosphatase increased
- Bradycardia (abnormally slow heart action)
- Coma (state of unconsciousness lasting more than six hours)
- Dizziness
- Drug ineffective
- Dysphagia (a condition in which swallowing is difficult or painful)
- Lacunar infarction (a type of stroke)
60+:
- Abdominal pain
- Asthenia (weakness)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Infusion site pain
- Loss of consciousness
- Malaise (a feeling of general discomfort or uneasiness)
- Poor venous access
- Weight decreased
What are the existing conditions these people have? *
- Failure To Thrive (inadequate weight gain and physical growth in children): 2 people, 16.67%
- T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 1 person, 8.33%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Purinethol and Flovent?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Purinethol (3,810 reports)
- Flovent (44,817 reports)
Browse all drug interactions of Purinethol and Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Purinethol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Purinethol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flovent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mercaptopurine and fluticasone propionate (the active ingredients of Purinethol and Flovent, respectively), and Purinethol and Flovent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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