Pyrazinamide and Cefuroxime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pyrazinamide (pyrazinamide) and Cefuroxime (cefuroxime sodium). Common drug interactions include aspartate aminotransferase increased among females and cachexia among males.

The phase IV clinical study analyzes what interactions people have when they take Pyrazinamide and Cefuroxime. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Pyrazinamide?

Pyrazinamide has active ingredients of pyrazinamide. It is often used in tuberculosis. eHealthMe is studying from 10,062 Pyrazinamide users. Check the latest studies of Pyrazinamide.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.

On Jul, 11, 2026

14 people who take Pyrazinamide and Cefuroxime together, and have interactions are studied.

Pyrazinamide and Cefuroxime drug interactions.

What are the common drug interactions of Pyrazinamide and Cefuroxime, by gender? *:

female:

Aspartate aminotransferase increased
Abortion spontaneous (naturally occurring miscarriage)
Alanine aminotransferase increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Complications of maternal exposure to therapeutic drugs
Drug level decreased
General physical health deterioration (weak health status)
Hepatotoxicity (chemical-driven liver damage)
Multi-organ failure (multisystem organ failure)

male:

Cachexia (loss of weight)
Decreased appetite
Arthralgia (joint pain)
Chest pain
Creatinine renal clearance decreased
Deafness
Dizziness
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Insomnia (sleeplessness)
Myalgia (muscle pain)

What are the common drug interactions of Pyrazinamide and Cefuroxime, by age (0-1 to 60+)? *:

0-1:

Hepatitis (inflammation of the liver)
Immune reconstitution syndrome (immune recovery syndrome)
Lymphadenitis (inflammation or enlargement of a lymph node)

2-9:

Cachexia (loss of weight)
Decreased appetite
Drug ineffective
Gastrointestinal obstruction
Tuberculosis gastrointestinal (a bacterial infection of digestive tract by mycobacterium tuberculosis)
Vomiting

10-19:

n/a

20-29:

Cat scratch disease (bacterial infection by cat scratch)
Abortion spontaneous (naturally occurring miscarriage)
Aspartate aminotransferase increased
Bleeding time prolonged
Blood iron decreased
Complications of maternal exposure to therapeutic drugs
General physical health deterioration (weak health status)
Haematoma (collection of blood outside the blood vessels)
Haematuria present (presence of blood in urine due to trauma)
Haemoglobin decreased

30-39:

Abdominal pain upper
Abdominal tenderness
Arthralgia (joint pain)
Chest pain
Creatinine renal clearance decreased
Deafness
Dizziness
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Insomnia (sleeplessness)
Myalgia (muscle pain)

40-49:

Multi-organ failure (multisystem organ failure)
Pulmonary tuberculosis (lungs tuberculosis)

50-59:

n/a

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Interstitial lung disease
Drug abuse
Drug level decreased
Dyspnoea (difficult or laboured respiration)
Hepatotoxicity (chemical-driven liver damage)
Lung disorder (lung disease)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)

What are the existing conditions these people have? *

Pneumonia: 6 people, 42.86%
Disseminated Tuberculosis: 4 people, 28.57%
Respiratory Tract Infection: 4 people, 28.57%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 14.29%
Vasculitis (inflammation of a blood vessel or blood vessels): 1 person, 7.14%
Interstitial Lung Disease: 1 person, 7.14%
Cd4 Lymphocytes Abnormal: 1 person, 7.14%
Escherichia Infection (bacterial infection by escherichia coli): 1 person, 7.14%
Fever: 1 person, 7.14%
Hiv Infection: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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