Q10 and Combigan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Q10 (coenzyme q - 10) and Combigan (brimonidine tartrate; timolol maleate). Common drug interactions include constipation among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Q10 and Combigan. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.
What is Q10?
Q10 has active ingredients of coenzyme q - 10. eHealthMe is studying from 34,261 Q10 users. Check the latest studies of Q10.
What is Combigan?
Combigan has active ingredients of brimonidine tartrate; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 7,810 Combigan users. Check the latest studies of Combigan.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
84 people who take Q10 and Combigan together, and have interactions are studied.

What are the common drug interactions of Q10 and Combigan, by gender? *:
female:
- Constipation
- Fall
- Herpes ophthalmic (eye infection caused by herpes simplex virus (hsv))
- Hot flush (sudden feelings of heat)
- Injection site bruising
- Pain
- Red blood cell count decreased
- Sinusitis (inflammation of sinus)
- Superficial injury of eye
- Visual impairment
male:
- Diarrhoea
- Fatigue (feeling of tiredness)
- Abdominal pain
- Acne (skin problems that cause pimples)
- Arthralgia (joint pain)
- Blood uric acid decreased
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Erythema (redness of the skin)
- Facial pain
- Feeling hot
What are the common drug interactions of Q10 and Combigan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Essential tremor
- Nephrolithiasis (calculi in the kidneys)
30-39:
n/a
40-49:
n/a
50-59:
- Depression
- Drug ineffective
- Emotional distress
- Fear
- Insomnia (sleeplessness)
- Lethargy (tiredness)
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain
- Renal failure (kidney dysfunction)
60+:
- Diarrhoea
- Fatigue (feeling of tiredness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Eye pain
- Hypertension (high blood pressure)
- Injury
- Mobility decreased (ability to move is reduced)
- Rash erythematous (redness of the skin)
- Abdominal pain upper
- Acne (skin problems that cause pimples)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 12 people, 14.29%
- Stress And Anxiety: 8 people, 9.52%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 8 people, 9.52%
- High Blood Cholesterol: 7 people, 8.33%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 8.33%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.14%
- Pain: 5 people, 5.95%
- Drowsiness: 5 people, 5.95%
* Approximation only. Some reports may have incomplete information.
Do you take Q10 and Combigan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Q10 and Combigan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Q10:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Combigan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Q10 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combigan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on coenzyme q - 10 and brimonidine tartrate; timolol maleate (the active ingredients of Q10 and Combigan, respectively), and Q10 and Combigan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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