Q10 and Xiaflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Q10 (coenzyme q - 10) and Xiaflex (collagenase clostridium histolyticum). Common drug interactions include colitis microscopic among females and drug effect decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Q10 and Xiaflex. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Q10?

Q10 has active ingredients of coenzyme q - 10. eHealthMe is studying from 34,261 Q10 users. Check the latest studies of Q10.

What is Xiaflex?

Xiaflex has active ingredients of collagenase clostridium histolyticum. eHealthMe is studying from 5,177 Xiaflex users. Check the latest studies of Xiaflex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

16 people who take Q10 and Xiaflex together, and have interactions are studied.

What are the common drug interactions of Q10 and Xiaflex, by gender? *:

female:

Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Peripheral swelling
Procedural pain

male:

Drug effect decreased
Flushing (the warm, red condition of human skin)
Scrotal swelling
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers)
Laceration (tearing of soft body tissue)
Swelling
Anxiety
Dizziness
Penile erythema (redness on penis)
Penile haematoma (localized collection of blood outside the blood vessels on penis)

What are the common drug interactions of Q10 and Xiaflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pain
Swelling

30-39:

n/a

40-49:

n/a

50-59:

Fracture of penis (rupture of one or both of covering)
Anxiety
Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Dizziness
Flushing (the warm, red condition of human skin)
Penile erythema (redness on penis)
Penile haematoma (localized collection of blood outside the blood vessels on penis)
Penile swelling
Peripheral swelling
Procedural pain

60+:

Injection site pain
Drug ineffective
Arthropathy
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Haemorrhage (bleeding)
Headache (pain in head)
Hypersensitivity
Laceration (tearing of soft body tissue)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphangitis (inflammation of the lymph channel)

What are the existing conditions these people have? *

Curvature Of The Penis: 10 people, 62.50%
Dupuytren's Contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers): 6 people, 37.50%
High Blood Pressure: 4 people, 25.00%
High Blood Cholesterol: 2 people, 12.50%
Pain: 1 person, 6.25%
Diabetes: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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