Questran and Demerol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Questran (cholestyramine) and Demerol (meperidine hydrochloride). Common drug interactions include musculoskeletal chest pain among females and blood creatine phosphokinase mb increased among males.

The phase IV clinical study analyzes what interactions people have when they take Questran and Demerol. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

On Jul, 14, 2026

14 people who take Questran and Demerol together, and have interactions are studied.

What are the common drug interactions of Questran and Demerol, by gender? *:

female:

Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pain in extremity
Arthralgia (joint pain)
Depression
Drug addiction
Fall

male:

Blood creatine phosphokinase mb increased
Cardiac enzymes increased
Disease progression
Heart rate increased
Intraventricular haemorrhage (intraventricular bleeding)
Nausea (feeling of having an urge to vomit)
Neuritis (inflammation of nerve)
Pyrexia (fever)
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Questran and Demerol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bipolar disorder (mood disorder)
Dependence
Depression
Drug abuser
Drug addiction
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Psychotic disorder

40-49:

Blood creatine phosphokinase mb increased
Cardiac enzymes increased
Chest pain
Chronic kidney disease
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Intraventricular haemorrhage (intraventricular bleeding)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

50-59:

Nausea (feeling of having an urge to vomit)
Neck pain
Neoplasm (tumour)
Neuritis (inflammation of nerve)
Obesity (having too much body fat)
Oedema peripheral (superficial swelling)
Cardiac disorder
Chest pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pyrexia (fever)

60+:

Pain in extremity
Arthralgia (joint pain)
Impaired healing
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Ligament disorder (disease of ligament)
Nausea (feeling of having an urge to vomit)
Precancerous skin lesion
Rash
Spinal column stenosis (narrowing of spinal column)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Oesophageal Candidiasis (fungal infection of oesophagus): 2 people, 14.29%
Stress And Anxiety: 1 person, 7.14%
Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 1 person, 7.14%
Arrhythmias (irregular heartbeat): 1 person, 7.14%
Birth Control: 1 person, 7.14%
Cardiac Failure Congestive: 1 person, 7.14%
Chest Pain: 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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