Questran and Lopid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Questran (cholestyramine) and Lopid (gemfibrozil). Common drug interactions include alanine aminotransferase increased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Questran and Lopid. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

51 people who take Questran and Lopid together, and have interactions are studied.

What are the common drug interactions of Questran and Lopid, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug hypersensitivity
Palpitations (feelings or sensations that your heart is pounding or racing)
Abdominal pain
Flatulence (flatus expelled through the anus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Abdominal pain upper
Anxiety
Blood immunoglobulin m increased

male:

Pain
Contusion (a type of hematoma of tissue in which capillaries)
Drug hypersensitivity
Infusion related reaction
Myalgia (muscle pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteosclerosis (an elevation in bone density)
Psoriasis (immune-mediated disease that affects the skin)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)

What are the common drug interactions of Questran and Lopid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

Chest pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Cardiovascular disorder (heart diseases)
Pneumonia legionella (pneumonia caused by the bacteria legionella)
Valvular heart disease (diseases of the heart valves)

40-49:

n/a

50-59:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Abdominal pain upper
Aseptic necrosis bone
Drug hypersensitivity
Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Influenza like illness
Infusion related reaction
Myalgia (muscle pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Flatulence (flatus expelled through the anus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Anxiety
Blood immunoglobulin m increased
Gammopathy (abnormal proliferation of the lymphoid cells producing immunoglobulins)
Headache (pain in head)
Intervertebral disc degeneration (spinal disc degeneration)
Lymphoma (cancer that begins in immune system cells)

What are the existing conditions these people have? *

Pain: 4 people, 7.84%
Neuralgia (pain in one or more nerves): 3 people, 5.88%
High Blood Pressure: 3 people, 5.88%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 5.88%
Chest Pain: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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