Quinine and Zocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Quinine (cinchona) and Zocor (simvastatin). Common drug interactions include blood creatinine increased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Quinine and Zocor. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Quinine?

Quinine has active ingredients of cinchona. It is often used in leg pain. eHealthMe is studying from 4,981 Quinine users. Check the latest studies of Quinine.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

On Jul, 20, 2026

42 people who take Quinine and Zocor together, and have interactions are studied.

What are the common drug interactions of Quinine and Zocor, by gender? *:

female:

Blood creatinine increased
Decreased interest
Dental care
Depression
Escherichia infection (bacterial infection by escherichia coli)
General physical health deterioration (weak health status)
Gingival disorder (gum disease)
Hyperlipidaemia (presence of excess lipids in the blood)
Impaired healing
Infection

male:

Pain
Anaemia (lack of blood)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Pneumonia
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Actinic elastosis (disorder in which the skin appears yellow and thickened as a result of sun damage)
Actinic keratosis (skin disease due to sun exposure)
Acute myocardial infarction (acute heart attack)

What are the common drug interactions of Quinine and Zocor, by age (0-1 to 60+)? *:

0-1:

Blood creatinine increased
Actinic elastosis (disorder in which the skin appears yellow and thickened as a result of sun damage)
Actinic keratosis (skin disease due to sun exposure)
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Myalgia (muscle pain)
Pain in extremity

50-59:

Cardiomyopathy (weakening of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Cough
Decreased appetite
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Diplopia (double vision)
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Fluid overload (too much fluid in the blood)

60+:

Pain
Bone disorder
Escherichia infection (bacterial infection by escherichia coli)
General physical health deterioration (weak health status)
Gingival disorder (gum disease)
Hyperlipidaemia (presence of excess lipids in the blood)
Impaired healing
Infection
Jaw disorder (jaw disease)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 8 people, 19.05%
Muscle Spasms (muscle contraction): 8 people, 19.05%
Breast Cancer: 8 people, 19.05%
Sleep Disorder: 7 people, 16.67%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 7 people, 16.67%
Depression: 7 people, 16.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.90%
High Blood Pressure: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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