Qulipta and Ajovy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Qulipta (atogepant) and Ajovy (fremanezumab-vfrm). Common drug interactions include constipation among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Qulipta and Ajovy. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Qulipta?

Qulipta has active ingredients of atogepant. eHealthMe is studying from 3,605 Qulipta users. Check the latest studies of Qulipta.

What is Ajovy?

Ajovy has active ingredients of fremanezumab-vfrm. eHealthMe is studying from 8,834 Ajovy users. Check the latest studies of Ajovy.



On Jul, 14, 2026

35 people who take Qulipta and Ajovy together, and have interactions are studied.

Qulipta and Ajovy drug interactions.

What are the common drug interactions of Qulipta and Ajovy, by gender? *:

female:

  1. Constipation
  2. Sleep disorder
  3. Surgery
  4. Acne (skin problems that cause pimples)
  5. Allergy to metals
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Asthenia (weakness)
  8. Bacterial infection
  9. Blood glucose fluctuation
  10. Blood glucose increased

male:

  1. Constipation

What are the common drug interactions of Qulipta and Ajovy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anxiety
  2. Constipation
  3. Injection site urticaria (rash of round, red welts on the skin at injection site)
  4. Suicidal ideation

30-39:

  1. Arthralgia (joint pain)
  2. Discomfort
  3. Head discomfort
  4. Neck pain
  5. Rash

40-49:

  1. Drug ineffective
  2. Migraine (headache)
  3. Cellulitis (infection under the skin)
  4. Pruritus (severe itching of the skin)
  5. Retching (strong involuntary effort to vomit)
  6. Rotator cuff repair
  7. Sleep disorder

50-59:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Asthenia (weakness)
  3. Bacterial infection
  4. Blood glucose fluctuation
  5. Blood glucose increased
  6. Bone pain
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Ear infection
  9. Ear infection bacterial
  10. Fatigue (feeling of tiredness)

60+:

  1. Constipation
  2. Fatigue (feeling of tiredness)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Migraine (headache)
  5. Rash

What are the existing conditions these people have? *

  1. Migraine (headache): 24 people, 68.57%
  2. Asthma: 4 people, 11.43%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.57%
  4. High Blood Pressure: 3 people, 8.57%
  5. Dry Eyes (lack of adequate tears): 2 people, 5.71%
  6. Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 2 people, 5.71%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.71%
  8. Gout (uric acid crystals building up in the body): 2 people, 5.71%
  9. High Blood Cholesterol: 2 people, 5.71%
  10. Urinary Tract Infection: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Qulipta and Ajovy?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Qulipta and Ajovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Qulipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ajovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Qulipta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ajovy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on atogepant and fremanezumab-vfrm (the active ingredients of Qulipta and Ajovy, respectively), and Qulipta and Ajovy (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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