Rabeprazole and Effexor xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Effexor xr (venlafaxine hydrochloride). Common drug interactions include depressed mood among females and benign prostatic hyperplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Effexor xr. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

On Aug, 03, 2026

29 people who take Rabeprazole and Effexor xr together, and have interactions are studied.

Rabeprazole and Effexor xr drug interactions.

What are the common drug interactions of Rabeprazole and Effexor Xr, by gender? *:

female:

Depressed mood
Emotional distress
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hepatitis (inflammation of the liver)
Hysterical psychosis (an acute psychosis accompanied by the symptoms of hysteria)
Ideas of reference
Leukopenia (less number of white blood cells in blood)
Mood swings (an extreme or rapid change in mood)
Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)

male:

Benign prostatic hyperplasia (benign enlargement of the prostate)
Asthma
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematemesis (vomiting of blood)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hepatic steatosis (fatty liver disease)
Herpes zoster
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

What are the common drug interactions of Rabeprazole and Effexor Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alcohol abuse
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
Borderline personality disorder
Cellulitis (infection under the skin)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug abuse
Dysthymic disorder (mild chronic depression disorder)
International normalised ratio increased
Joint sprain (an injury to joint surrounding flexible fibres)
Mitral valve incompetence (inefficient heart valve)

30-39:

Blood pressure increased
Herpes zoster

40-49:

n/a

50-59:

Abnormal dreams
Agitation (state of anxiety or nervous excitement)
Anger
Bipolar disorder (mood disorder)
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Cough
Crying
Drug dependence
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hepatic steatosis (fatty liver disease)

60+:

Intentional self-injury
Psychotic disorder
Constipation
Cyclothymic disorder (mood disorder)
Delusion (a false belief or opinion)
Depressed mood
Emotional distress
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hepatitis (inflammation of the liver)
Hypomania (a mild form of mania, marked by elation and hyperactivity)

What are the existing conditions these people have? *

Birth Control: 4 people, 13.79%
Bipolar Disorder (mood disorder): 3 people, 10.34%
Stress And Anxiety: 2 people, 6.90%
Post-Traumatic Stress Disorder: 2 people, 6.90%
Hiv Infection: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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