Rabeprazole and Epinastine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Epinastine hydrochloride (epinastine hydrochloride). Common drug interactions include laryngeal oedema among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Epinastine hydrochloride. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Epinastine hydrochloride?

Epinastine hydrochloride has active ingredients of epinastine hydrochloride. eHealthMe is studying from 1,582 Epinastine hydrochloride users. Check the latest studies of Epinastine hydrochloride.

On Jul, 28, 2026

51 people who take Rabeprazole and Epinastine hydrochloride together, and have interactions are studied.

Rabeprazole and Epinastine hydrochloride drug interactions.

What are the common drug interactions of Rabeprazole and Epinastine Hydrochloride, by gender? *:

female:

Laryngeal oedema (swelling of larynx)
Anaphylactic reaction (serious allergic reaction)
C-reactive protein increased
Pneumonia
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Pyrexia (fever)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Subcutaneous haematoma (collection of blood outside the blood vessels on the skin)
Therapeutic response decreased (less preventive response)
Eosinophil count increased

male:

Malaise (a feeling of general discomfort or uneasiness)
Decreased appetite
Oedema (fluid collection in tissue)
Tonsillitis (inflammation of tonsil)
Weight increased
Cardiomyopathy (weakening of the heart muscle)
Arthralgia (joint pain)
Cardiac failure congestive
Cardiogenic shock (inadequate circulation of blood)
Ear discomfort

What are the common drug interactions of Rabeprazole and Epinastine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pneumonia
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Pyrexia (fever)
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)

30-39:

Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Blood creatine phosphokinase increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug effect decreased
Hypokalaemia (low potassium)
Myalgia (muscle pain)
Arthralgia (joint pain)
Gait disturbance

40-49:

Ear discomfort
Sudden hearing loss
Tinnitus (a ringing in the ears)
Eosinophil count increased
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Rash
Anaphylactic reaction (serious allergic reaction)
Laryngeal oedema (swelling of larynx)

50-59:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Second primary malignancy (after getting cure a cancer, a new cancer development)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Cushing's syndrome (obesity, a rounded face, increased fat)
Cushingoid (obesity and weakening of the muscles)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Haemoglobin decreased
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Infection

60+:

Decreased appetite
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Malaise (a feeling of general discomfort or uneasiness)
Optic neuritis (optic nerve inflammation)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Subcutaneous haematoma (collection of blood outside the blood vessels on the skin)
Therapeutic response decreased (less preventive response)
Toxic skin eruption (skin breakdown due to toxic substance)
Anaemia (lack of blood)
Blood pressure increased

What are the existing conditions these people have? *

Back Pain: 15 people, 29.41%
Seasonal Allergy (allergic condition due to certain season): 10 people, 19.61%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 17.65%
Insomnia (sleeplessness): 8 people, 15.69%
Multiple Myeloma (cancer of the plasma cells): 8 people, 15.69%
Thyroxine Free Increased: 7 people, 13.73%
Gastric Ulcer (stomach ulcer): 7 people, 13.73%
High Blood Pressure: 7 people, 13.73%
Muscle Spasms (muscle contraction): 7 people, 13.73%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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