Rabeprazole and Tysabri drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Tysabri (natalizumab). Common drug interactions include campylobacter gastroenteritis among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Tysabri. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.



On Jul, 11, 2026

20 people who take Rabeprazole and Tysabri together, and have interactions are studied.

Rabeprazole and Tysabri drug interactions.

What are the common drug interactions of Rabeprazole and Tysabri, by gender? *:

female:

  1. Campylobacter gastroenteritis (infection of gastrointestinal system)
  2. Chest discomfort
  3. Constipation
  4. Cough
  5. Depression
  6. Dyspepsia (indigestion)
  7. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  8. Flatulence (flatus expelled through the anus)
  9. Gallbladder disorder
  10. Hemicephalalgia (headache affecting one side of the head)

male:

  1. Balance disorder
  2. Abdominal distension
  3. Infection
  4. Insomnia (sleeplessness)
  5. Nausea (feeling of having an urge to vomit)
  6. Pathogen resistance
  7. Pleural effusion (water on the lungs)
  8. Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
  9. Renal impairment (severely reduced kidney function)
  10. Weight increased

What are the common drug interactions of Rabeprazole and Tysabri, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Mobility decreased (ability to move is reduced)
  2. Oral herpes (viral infection of mouth)
  3. Ovarian neoplasm (tumour of ovary)
  4. Peripheral coldness
  5. Sensory disturbance (sense disturbance)
  6. Urticaria (rash of round, red welts on the skin that itch intensely)
  7. Ascites (accumulation of fluid in the abdominal cavity)
  8. Blood pressure decreased
  9. Campylobacter gastroenteritis (infection of gastrointestinal system)
  10. Hypersensitivity

30-39:

  1. Cholecystitis (infection of gallbladder)
  2. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  3. Chest pain
  4. Confusional state
  5. Cytolytic hepatitis (dissolution or destruction of a liver cell)
  6. Dizziness
  7. Eye movement disorder
  8. Eyelid ptosis (falling of the upper or lower eyelid)
  9. Iiird nerve disorder
  10. Iiird nerve paralysis (totally closed eyelid and a down and out deviation of the eye)

40-49:

  1. Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
  2. Abdominal distension
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  5. Balance disorder
  6. Decreased appetite
  7. Dehydration (dryness resulting from the removal of water)
  8. Disease progression
  9. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  10. Hypophagia (reduced food intake)

50-59:

  1. Adhesion
  2. Constipation
  3. Dyspepsia (indigestion)
  4. Flatulence (flatus expelled through the anus)
  5. Gallbladder disorder
  6. Nausea (feeling of having an urge to vomit)
  7. Volvulus (obstruction caused by twisting of the stomach or intestine)

60+:

  1. Cerebral haemorrhage (bleeding within the brain)
  2. Gait disturbance
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Confusional state
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Death
  7. Diarrhoea haemorrhagic (bloody diarrhoea)
  8. Dilatation intrahepatic duct acquired
  9. Dizziness
  10. Dysstasia (difficulty in standing)

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 25.00%
  2. High Blood Cholesterol: 3 people, 15.00%
  3. Depression: 2 people, 10.00%
  4. Abdominal Pain Upper: 2 people, 10.00%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.00%
  7. Pseudotumor Cerebri (increased pressure within the brain in the absence of a tumour): 1 person, 5.00%
  8. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 5.00%
  9. Age-Related Macular Degeneration: 1 person, 5.00%
  10. Constipation: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rabeprazole and Tysabri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tysabri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rabeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tysabri and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium and natalizumab (the active ingredients of Rabeprazole and Tysabri, respectively), and Rabeprazole and Tysabri (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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