Rabeprazole and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Zelnorm (tegaserod maleate). Common drug interactions include malaise among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Zelnorm. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.



On Jul, 08, 2026

12 people who take Rabeprazole and Zelnorm together, and have interactions are studied.

Rabeprazole and Zelnorm drug interactions.

What are the common drug interactions of Rabeprazole and Zelnorm, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Chest pain
  3. Circulatory collapse
  4. Coronary artery dilatation
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  7. Dizziness
  8. Dyspnoea (difficult or laboured respiration)
  9. Electrocardiogram qt prolonged
  10. Electrocardiogram st segment elevation

male:

  1. Constipation

What are the common drug interactions of Rabeprazole and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Acute myocardial infarction (acute heart attack)
  2. Anxiety
  3. Artery dissection
  4. Asthenia (weakness)
  5. Blood creatine phosphokinase increased
  6. Cardiac enzymes increased
  7. Chest discomfort
  8. Chest pain
  9. Circulatory collapse
  10. Coronary artery dilatation

40-49:

  1. Mouth ulceration (mouth ulcers)
  2. Oedema mouth (swelling of mouth)
  3. Oral discomfort (pain or irritation in mouth)
  4. Oral pain
  5. Oral pruritus (itching in mouth)
  6. Biliary colic
  7. Abdominal pain
  8. Dehydration (dryness resulting from the removal of water)
  9. Diarrhoea
  10. Flatulence (flatus expelled through the anus)

50-59:

  1. Constipation
  2. Abdominal distension
  3. Abdominal pain upper
  4. Faecaloma (hard mass of fecal matter)

60+:

n/a

What are the existing conditions these people have? *

  1. Irritable Bowel Syndrome: 7 people, 58.33%
  2. Migraine (headache): 3 people, 25.00%
  3. Acne (skin problems that cause pimples): 3 people, 25.00%
  4. Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 2 people, 16.67%
  5. Vasculitis (inflammation of a blood vessel or blood vessels): 1 person, 8.33%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
  7. Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
  8. High Blood Cholesterol: 1 person, 8.33%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%
  10. Candidiasis (candidiasis or thrush is a fungal infection): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Rabeprazole and Zelnorm?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rabeprazole and Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rabeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zelnorm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium and tegaserod maleate (the active ingredients of Rabeprazole and Zelnorm, respectively), and Rabeprazole and Zelnorm (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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