Rabeprazole and Zemplar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Zemplar (paricalcitol). Common drug interactions include azotaemia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Zemplar. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.

On Aug, 03, 2026

11 people who take Rabeprazole and Zemplar together, and have interactions are studied.

Rabeprazole and Zemplar drug interactions.

What are the common drug interactions of Rabeprazole and Zemplar, by gender? *:

female:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arrhythmia (irregular heartbeat)
Asthma
Blood triglycerides increased
Cardiogenic shock (inadequate circulation of blood)
Cardiomyopathy (weakening of the heart muscle)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Rabeprazole and Zemplar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Pyrexia (fever)
Respiratory tract infection
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal failure (kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Acute myocardial infarction (acute heart attack)
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the existing conditions these people have? *

Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 5 people, 45.45%
High Blood Pressure: 3 people, 27.27%
Pain: 3 people, 27.27%
Indigestion: 3 people, 27.27%
Gastric Ulcer (stomach ulcer): 2 people, 18.18%
Chronic Renal Failure (kidney failure): 2 people, 18.18%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 18.18%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 18.18%
Thyroid Diseases: 2 people, 18.18%
High Blood Cholesterol: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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