Ramelteon and Zosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ramelteon (ramelteon) and Zosyn (piperacillin sodium; tazobactam sodium). Common drug interactions include anaemia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ramelteon and Zosyn. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ramelteon?

Ramelteon has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 1,387 Ramelteon users. Check the latest studies of Ramelteon.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

On Jul, 11, 2026

13 people who take Ramelteon and Zosyn together, and have interactions are studied.

What are the common drug interactions of Ramelteon and Zosyn, by gender? *:

female:

Anaemia (lack of blood)
Cerebral atrophy (decrement in size of brain)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Oliguria (not enough urine)
Oropharyngeal candidiasis (fungal infection of oropharynx)
Thrombocytopenia (decrease of platelets in blood)
Device related infection
Hypophagia (reduced food intake)
Altered state of consciousness (altered state of mind)
Catheter site infection (infection at the site of insertion)

male:

Febrile neutropenia (fever with reduced white blood cells)
Cerebral haemorrhage (bleeding within the brain)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Injection site reaction
Myocardiac abscess (a pus containing infection of myocardium)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oral herpes (viral infection of mouth)
Pericarditis (inflammation of the pericardium)
Rash

What are the common drug interactions of Ramelteon and Zosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Febrile neutropenia (fever with reduced white blood cells)
Anaemia (lack of blood)
Hypophagia (reduced food intake)
Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Road traffic accident
Spinal compression fracture (fracture due to spinal compression on bone)
Altered state of consciousness (altered state of mind)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
C-reactive protein increased

What are the existing conditions these people have? *

Rashes (redness): 3 people, 23.08%
Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 3 people, 23.08%
Cerebral Atrophy (decrement in size of brain): 3 people, 23.08%
Dyslipidaemia (abnormal amount of lipids): 2 people, 15.38%
Lung Squamous Cell Carcinoma Stage Iv (the lung cancer has spread to the other lung, and/or to lymph nodes, fluid around the lungs or heart, and/or other places in the body, such as the brain, liver, adrenal glands, kidneys, or bones): 2 people, 15.38%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 15.38%
High Blood Pressure: 2 people, 15.38%
Pain: 2 people, 15.38%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 15.38%
Immunodeficiency Disorders: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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