Ranexa and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranexa (ranolazine) and Exforge (amlodipine besylate; valsartan). Common drug interactions include arthritis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Ranexa and Exforge. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

On Aug, 02, 2026

16 people who take Ranexa and Exforge together, and have interactions are studied.

What are the common drug interactions of Ranexa and Exforge, by gender? *:

female:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Aortic valve stenosis (narrowing of the aortic valve)
Cardiomegaly (increased size of heart than normal)
Dizziness
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypersomnia (excessive daytime sleepiness (eds))

male:

Pneumonia
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cough
Dyspnoea (difficult or laboured respiration)
Joint swelling
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pleural effusion (water on the lungs)
Pneumonia necrotising (necrotizing pneumonia is a life-threatening condition in which a person breathes material into his or her lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)

What are the common drug interactions of Ranexa and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

50-59:

n/a

60+:

Pneumonia
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cough
Dyspnoea (difficult or laboured respiration)
Joint swelling
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pleural effusion (water on the lungs)
Pneumonia necrotising (necrotizing pneumonia is a life-threatening condition in which a person breathes material into his or her lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 9 people, 56.25%
High Blood Pressure: 3 people, 18.75%
Stable Angina (a constant chest pain): 2 people, 12.50%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 12.50%
Type 2 Diabetes: 1 person, 6.25%
Thyroid Cancer: 1 person, 6.25%
Pain: 1 person, 6.25%
Infection: 1 person, 6.25%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.25%
High Blood Cholesterol: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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