Ranexa and Lovenox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ranexa (ranolazine) and Lovenox (enoxaparin sodium). Common drug interactions include intestinal ischaemia among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Ranexa and Lovenox. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.
What is Ranexa?
Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.
What is Lovenox?
Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.
51 people who take Ranexa and Lovenox together, and have interactions are studied.

What are the common drug interactions of Ranexa and Lovenox, by gender? *:
female:
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Joint swelling
- Metastases to bone (cancer spreads to bone)
- Metastases to meninges (cancer spreads to meninges)
- Monoplegia (a paralysis of a single limb)
- Neoplasm progression (growth of tumour)
- Neuralgia (pain in one or more nerves)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Alanine aminotransferase decreased
male:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Cardiac disorder
- Cardiac failure congestive
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
- Depression
- Fear
What are the common drug interactions of Ranexa and Lovenox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia (lack of blood)
- Epistaxis (bleed from the nose)
- Gastritis (inflammation of stomach)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Melaena (the passage of black, tarry stools)
- Thrombosis (formation of a blood clot inside a blood vessel)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Oedema peripheral (superficial swelling)
- Postnasal drip
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Wheezing (a high-pitched whistling sound made while you breath)
- Abdominal pain
- Nausea (feeling of having an urge to vomit)
60+:
- Gout (uric acid crystals building up in the body)
- Upper respiratory tract infection
- Conjunctival haemorrhage (bleeding underneath the conjunctiva)
- Depression
- Injury
- Mouth haemorrhage (bleeding from mouth)
- Pain
- Renal impairment (severely reduced kidney function)
- Acute myocardial infarction (acute heart attack)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the existing conditions these people have? *
- High Blood Pressure: 15 people, 29.41%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 21.57%
- Stable Angina (a constant chest pain): 10 people, 19.61%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 19.61%
- Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 17.65%
- Heart Attack: 8 people, 15.69%
- Nausea (feeling of having an urge to vomit): 8 people, 15.69%
- Cardiac Failure: 7 people, 13.73%
- Oral Candidiasis (fungal infection of mouth): 7 people, 13.73%
- Chronic Lymphocytic Leukaemia Stage 4 (blood cell cancer with too few blood platelets), with or without anaemia, enlarged lymph nodes, spleen, or liver): 7 people, 13.73%
* Approximation only. Some reports may have incomplete information.
Do you take Ranexa and Lovenox?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ranexa and Lovenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ranexa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lovenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ranexa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lovenox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ranolazine and enoxaparin sodium (the active ingredients of Ranexa and Lovenox, respectively), and Ranexa and Lovenox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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