Ranexa and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranexa (ranolazine) and Vimpat (lacosamide). Common drug interactions include hereditary angioedema among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Ranexa and Vimpat. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

On Jul, 11, 2026

51 people who take Ranexa and Vimpat together, and have interactions are studied.

What are the common drug interactions of Ranexa and Vimpat, by gender? *:

female:

Hereditary angioedema (recurrent episodes of severe swelling)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cardiac infection (an infection of the heart)
Depressed mood
Fall
Herpes zoster
Infusion site infection
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Balance disorder
Cardiac valve vegetation (heart valve abnormal growth)

male:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Brain stem ischaemia (a condition in which there is insufficient blood flow to the brain to meet metabolic demand)
Syncope (loss of consciousness with an inability to maintain postural tone)
Cerebral haemorrhage (bleeding within the brain)
Gait disturbance
Asthenia (weakness)
Chronic kidney disease
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the common drug interactions of Ranexa and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hereditary angioedema (recurrent episodes of severe swelling)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cardiac infection (an infection of the heart)
Depressed mood
Infusion site infection
Cardiac valve vegetation (heart valve abnormal growth)
Dehydration (dryness resulting from the removal of water)
Device related infection
Thrombosis (formation of a blood clot inside a blood vessel)
Upper respiratory tract infection

40-49:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Fall
Fungal skin infection
Hypokalaemia (low potassium)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Urinary tract infection bacterial
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Hereditary angioedema (recurrent episodes of severe swelling)

50-59:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cerebral haemorrhage (bleeding within the brain)
Diarrhoea
Fall
Fungal skin infection
Hypokalaemia (low potassium)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Urinary tract infection bacterial
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

60+:

Dizziness
Brain stem ischaemia (a condition in which there is insufficient blood flow to the brain to meet metabolic demand)
Balance disorder
Bradycardia (abnormally slow heart action)
Cerebral haemorrhage (bleeding within the brain)
Chronic kidney disease
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 25 people, 49.02%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 13.73%
High Blood Pressure: 7 people, 13.73%
Stress And Anxiety: 6 people, 11.76%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 9.80%
Insomnia (sleeplessness): 4 people, 7.84%
Gout (uric acid crystals building up in the body): 4 people, 7.84%
High Blood Cholesterol: 4 people, 7.84%
Constipation: 4 people, 7.84%
Carotid Artery Disease: 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

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