Ranitidine hydrochloride and Zosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine hydrochloride (ranitidine hydrochloride) and Zosyn (piperacillin sodium; tazobactam sodium). Common drug interactions include abdominal pain upper among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine hydrochloride and Zosyn. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine hydrochloride?

Ranitidine hydrochloride has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 76,413 Ranitidine hydrochloride users. Check the latest studies of Ranitidine hydrochloride.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

On Jul, 15, 2026

16 people who take Ranitidine hydrochloride and Zosyn together, and have interactions are studied.

Ranitidine hydrochloride and Zosyn drug interactions.

What are the common drug interactions of Ranitidine Hydrochloride and Zosyn, by gender? *:

female:

Abdominal pain upper
Disease progression
Abdominal pain
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Chest pain
Malaise (a feeling of general discomfort or uneasiness)
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

Anxiety
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Ascites (accumulation of fluid in the abdominal cavity)
Bone density decreased
Bone pain
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Constipation
Emotional distress
Muscle spasms (muscle contraction)
Pain

What are the common drug interactions of Ranitidine Hydrochloride and Zosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Death
Emotional distress
Pain
Renal failure (kidney dysfunction)
Tooth loss

30-39:

Anal abscess
Cellulitis (infection under the skin)
Genital abscess (build up of pus in genital)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Scrotal abscess (pus in scrotum)
Scrotal oedema (swelling of scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Testicular necrosis (damaged testes)
Urinary tract infection

40-49:

n/a

50-59:

Abdominal pain
Atelectasis (partial or complete collapse of the lung)
Blood potassium decreased
Colitis (inflammation of colon)
Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
Diarrhoea
Mucosal inflammation (infection of mucous membrane)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nausea (feeling of having an urge to vomit)
Oesophagitis (inflammation of oesophagus)

60+:

Pyrexia (fever)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Bone pain
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Constipation
Muscle spasms (muscle contraction)
Post procedural bile leak
Sepsis (a severe blood infection that can lead to organ failure and death)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 3 people, 18.75%
Gastric Ulcer (stomach ulcer): 3 people, 18.75%
Hyperglycemia (high blood sugar): 3 people, 18.75%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 18.75%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 3 people, 18.75%
Fungal Infection: 3 people, 18.75%
Immunodeficiency Disorders: 3 people, 18.75%
Iron Deficiency Anaemia: 3 people, 18.75%
Folate Deficiency (lack of folic acid): 3 people, 18.75%
Fever: 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine hydrochloride and Zosyn?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously