Ranitidine and Cosopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine (ranitidine) and Cosopt (dorzolamide hydrochloride; timolol maleate). Common drug interactions include disease progression among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine and Cosopt. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

On Jul, 06, 2026

49 people who take Ranitidine and Cosopt together, and have interactions are studied.

Ranitidine and Cosopt drug interactions.

What are the common drug interactions of Ranitidine and Cosopt, by gender? *:

female:

Disease progression
Drug ineffective
Eye irritation
Eyelid pain
Faecal incontinence (a lack of control over passing stool)
Fall
Hallucination, visual (seeing things that aren't there)
Hip fracture
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity

male:

Renal failure (kidney dysfunction)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
General physical health deterioration (weak health status)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Retching (strong involuntary effort to vomit)
Angioplasty
Blindness unilateral
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood pressure increased
Corneal scar (nullah)

What are the common drug interactions of Ranitidine and Cosopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Renal tubular necrosis (death of kidney tubules)
Transaminases increased
Wheezing (a high-pitched whistling sound made while you breath)
Abdominal distension
Acute respiratory failure
Anxiety
Bacterial infection
Blood creatinine increased
Cardiac arrest
Hyperchloraemia (an excess of chlorides in the blood)

30-39:

n/a

40-49:

Bursitis infective (the bursa can become infected, this is called infected bursitis)

50-59:

Conjunctivitis (pink eye)
Ear congestion
Eye discharge
Eye haemorrhage (bleeding in the eye)
Eye infection viral
Eye pain
Growth of eyelashes
Lacrimation increased
Pain
Pyrexia (fever)

60+:

Nausea (feeling of having an urge to vomit)
Pain
Chronic kidney disease
General physical health deterioration (weak health status)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Retching (strong involuntary effort to vomit)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Anaphylactic reaction (serious allergic reaction)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 12.24%
Stable Angina (a constant chest pain): 4 people, 8.16%
Osteoporosis (bones weak and more likely to break): 4 people, 8.16%
High Blood Pressure: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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