Ranitidine and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine (ranitidine) and Exforge (amlodipine besylate; valsartan). Common drug interactions include gastritis among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine and Exforge. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.



On Jul, 23, 2026

79 people who take Ranitidine and Exforge together, and have interactions are studied.

Ranitidine and Exforge drug interactions.

What are the common drug interactions of Ranitidine and Exforge, by gender? *:

female:

  1. Gastritis (inflammation of stomach)
  2. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  3. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  4. Road traffic accident
  5. Vomiting
  6. Anxiety
  7. Brain mass
  8. Fatigue (feeling of tiredness)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Memory impairment

male:

  1. Chest pain
  2. Infarction (obstruction of the blood supply to an organ or region of tissue)
  3. Cardiac valve sclerosis (heart valve thickness)
  4. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  5. Coronary artery stenosis (narrowing of coronary artery)
  6. Diastolic dysfunction
  7. Eosinophil count increased
  8. Fatigue (feeling of tiredness)
  9. Functional residual capacity decreased
  10. Haemoglobin decreased

What are the common drug interactions of Ranitidine and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Decreased activity
  5. Depression
  6. Emotional distress
  7. Impaired work ability
  8. Pain
  9. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  10. Renal failure (kidney dysfunction)

40-49:

  1. Ankle fracture
  2. Chronic kidney disease
  3. Fall
  4. Fibula fracture
  5. Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
  6. Lower limb fracture
  7. Nerve injury
  8. Osteoporosis (bones weak and more likely to break)
  9. Renal failure (kidney dysfunction)
  10. Renal injury (kidney injury)

50-59:

  1. Brain mass
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fall
  6. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Hypervolaemia (abnormally increased volume of blood)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Immune system disorder

60+:

  1. Chest pain
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Blood sodium increased
  4. Cardiac valve sclerosis (heart valve thickness)
  5. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  6. Coronary artery stenosis (narrowing of coronary artery)
  7. Diastolic dysfunction
  8. Eosinophil count increased
  9. Functional residual capacity decreased
  10. Haemoglobin decreased

What are the existing conditions these people have? *

  1. High Blood Pressure: 39 people, 49.37%
  2. High Blood Cholesterol: 20 people, 25.32%
  3. Diabetes: 15 people, 18.99%
  4. Pain: 14 people, 17.72%
  5. Indigestion: 10 people, 12.66%
  6. Asthma: 8 people, 10.13%
  7. Depression: 8 people, 10.13%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 8 people, 10.13%
  9. Osteoporosis (bones weak and more likely to break): 7 people, 8.86%
  10. Cardiac Disorder: 7 people, 8.86%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and Exforge?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ranitidine and Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ranitidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine and amlodipine besylate; valsartan (the active ingredients of Ranitidine and Exforge, respectively), and Ranitidine and Exforge (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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