Ranitidine and Fluoride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine (ranitidine) and Fluoride (fluoride). Common drug interactions include blood alkaline phosphatase increased among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine and Fluoride. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

On Aug, 09, 2026

41 people who take Ranitidine and Fluoride together, and have interactions are studied.

Ranitidine and Fluoride drug interactions.

What are the common drug interactions of Ranitidine and Fluoride, by gender? *:

female:

Blood alkaline phosphatase increased
Blood bilirubin increased
Blood calcium decreased
Blood cholesterol increased
Blood creatine phosphokinase increased
Blood iron decreased
Blood urea decreased
Blood urine present
Bone density decreased
Burning sensation

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Subdural empyema (collection of supportive material between the dura mater and arachnoids surrounding the brain)
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Urinary tract infection
Alanine aminotransferase increased
Anxiety
Aspartate aminotransferase increased
Blood bilirubin increased

What are the common drug interactions of Ranitidine and Fluoride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Vomiting
White blood cell count decreased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Pyrexia (fever)
Anaemia (lack of blood)
Cough
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)

10-19:

Encephalitis (inflammation of the brain)
Mastoiditis (infection of mastoid bone)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)
Subdural empyema (collection of supportive material between the dura mater and arachnoids surrounding the brain)
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Chronic kidney disease
Influenza
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

20-29:

Hepatobiliary disease (diseases affect the liver and/or biliary tract)

30-39:

n/a

40-49:

n/a

50-59:

Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Nausea (feeling of having an urge to vomit)
Alanine aminotransferase increased
Back pain
Chills (felling of cold)
Constipation
Faecaloma (hard mass of fecal matter)
Gastroenteritis (inflammation of stomach and intestine)
Hepatic steatosis (fatty liver disease)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Muscle rupture (tear in muscle)
Neuropathy peripheral (surface nerve damage)
Pain
Platelet count decreased
Tracheomalacia (a structural abnormality of the tracheal (windpipe) cartilage resulting in the collapse of the wall of the trachea which obstructs the airway)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Dry mouth

What are the existing conditions these people have? *

Pain: 7 people, 17.07%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 17.07%
Hypersensitivity: 6 people, 14.63%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 12.20%
Neuropathy Peripheral (surface nerve damage): 3 people, 7.32%
Nausea (feeling of having an urge to vomit): 3 people, 7.32%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 7.32%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.32%
High Blood Pressure: 3 people, 7.32%
Cough: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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