Ranitidine and Lotronex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine (ranitidine) and Lotronex (alosetron hydrochloride). Common drug interactions include back pain among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine and Lotronex. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Lotronex?

Lotronex has active ingredients of alosetron hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 6,841 Lotronex users. Check the latest studies of Lotronex.

On Aug, 08, 2026

15 people who take Ranitidine and Lotronex together, and have interactions are studied.

Ranitidine and Lotronex drug interactions.

What are the common drug interactions of Ranitidine and Lotronex, by gender? *:

female:

Back pain
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Nausea (feeling of having an urge to vomit)
Abdominal distension
Abdominal pain lower
Anal sphincter atony (anal muscles are weak and cannot ensure an efficient sealing, this is called a sphincter atony)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Fluid overload (too much fluid in the blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

male:

Anxiety
Dizziness
Emotional distress
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Renal failure (kidney dysfunction)

What are the common drug interactions of Ranitidine and Lotronex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dry mouth

30-39:

Abdominal pain upper
Anal fissure
Constipation
Diarrhoea
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Impaired healing
Liver fatty (fat deposition of liver)
Micturition disorder (disease of passing urine)
Perirectal abscess
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

40-49:

n/a

50-59:

Acute respiratory distress syndrome
Anal sphincter atony (anal muscles are weak and cannot ensure an efficient sealing, this is called a sphincter atony)
Back pain
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Fluid overload (too much fluid in the blood)
Intervertebral disc herniation (spinal disc herniation)
Oral candidiasis (fungal infection of mouth)
Pulmonary oedema (fluid accumulation in the lungs)

60+:

Abdominal pain upper
Abdominal distension
Colitis (inflammation of colon)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Colonic perforation (a hole in the colon)
Constipation
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 2 people, 13.33%
Vitamin D Decreased: 1 person, 6.67%
Skin Hyperpigmentation (disorders affect the colour of your skin): 1 person, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%
High Blood Cholesterol: 1 person, 6.67%
Gastric Ulcer (stomach ulcer): 1 person, 6.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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