Ranitidine and Thiotepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine (ranitidine) and Thiotepa (thiotepa). Common drug interactions include pain among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine and Thiotepa. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Thiotepa?

Thiotepa has active ingredients of thiotepa. eHealthMe is studying from 8,097 Thiotepa users. Check the latest studies of Thiotepa.

On Aug, 12, 2026

59 people who take Ranitidine and Thiotepa together, and have interactions are studied.

Ranitidine and Thiotepa drug interactions.

What are the common drug interactions of Ranitidine and Thiotepa, by gender? *:

female:

Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Rash erythematous (redness of the skin)
Visual impairment
Diarrhoea
Gamma-glutamyltransferase increased
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Hypotension (abnormally low blood pressure)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Diarrhoea
Mucosal inflammation (infection of mucous membrane)
Presyncope
Pyrexia (fever)
Respiratory distress (difficulty in breathing)
Venoocclusive liver disease (small veins in the liver are obstructed)
Vomiting
Multi-organ failure (multisystem organ failure)
Abdominal distension
Alopecia (absence of hair from areas of the body)

What are the common drug interactions of Ranitidine and Thiotepa, by age (0-1 to 60+)? *:

0-1:

Abdominal distension
Alopecia (absence of hair from areas of the body)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Candidiasis (candidiasis or thrush is a fungal infection)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Failure to thrive (inadequate weight gain and physical growth in children)
Fluid overload (too much fluid in the blood)
Gastroenteritis (inflammation of stomach and intestine)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)

2-9:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Bacteraemia (presence of bacteria in the blood)
Epstein-barr virus infection
Diarrhoea
Aplasia (defective development or congenital absence of an organ or tissue)
Epistaxis (bleed from the nose)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Thrombocytopenia (decrease of platelets in blood)
Acute respiratory failure
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

10-19:

Presyncope
Abdominal pain
Acute respiratory failure
Aplasia (defective development or congenital absence of an organ or tissue)
Cytomegalovirus infection
Diarrhoea
Epistaxis (bleed from the nose)
Pulmonary mass
Vomiting
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)

20-29:

Ascites (accumulation of fluid in the abdominal cavity)
Cardiac arrest
Enteritis (inflammation of the small intestine)
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mucosal inflammation (infection of mucous membrane)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain
Central line infection (infection by central line in icu)
Diarrhoea

30-39:

n/a

40-49:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Diarrhoea
Drug clearance increased
Drug level below therapeutic
Haematuria present (presence of blood in urine due to trauma)
Mucosal inflammation (infection of mucous membrane)
Scar
Stem cell transplant

50-59:

Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Capillaritis (inflamed capillaries under the skin)
Hepatitis (inflammation of the liver)
Mucosal inflammation (infection of mucous membrane)

60+:

Blood creatinine decreased
Creatinine renal clearance increased
Faecal incontinence (a lack of control over passing stool)
Muscular weakness (muscle weakness)
Oedema peripheral (superficial swelling)
Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 19 people, 32.20%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 7 people, 11.86%
Drug Dependence: 5 people, 8.47%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 6.78%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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