Ranolazine and Actos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranolazine (ranolazine) and Actos (pioglitazone hydrochloride). Common drug interactions include asthma among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Ranolazine and Actos. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

On Jul, 14, 2026

22 people who take Ranolazine and Actos together, and have interactions are studied.

What are the common drug interactions of Ranolazine and Actos, by gender? *:

female:

Asthma
Non-cardiac chest pain
Suicidal ideation
Depression
Reflux gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile)
Renal failure acute (rapid kidney dysfunction)
Gastritis (inflammation of stomach)
Abdominal pain
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)

male:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Multiple fractures
Muscle twitching
Muscular weakness (muscle weakness)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Spinal compression fracture (fracture due to spinal compression on bone)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the common drug interactions of Ranolazine and Actos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back disorder
Chest pain
Insomnia (sleeplessness)
Joint injury
Multiple fractures
Muscle twitching
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Spinal compression fracture (fracture due to spinal compression on bone)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Abdominal tenderness
Cardiac disorder
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery restenosis (recurrence of narrowing of artery)
Cough
Depression
Diarrhoea
Dizziness postural

60+:

Asthma
Non-cardiac chest pain
Weight decreased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypoaesthesia (reduced sense of touch or sensation)
Lung disorder (lung disease)
Muscular weakness (muscle weakness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the existing conditions these people have? *

Type 2 Diabetes: 10 people, 45.45%
Stable Angina (a constant chest pain): 8 people, 36.36%
High Blood Pressure: 4 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
Abdominal Discomfort: 3 people, 13.64%
Pain: 3 people, 13.64%
Infection: 3 people, 13.64%
Multiple Allergies (allergy to multiple agents): 3 people, 13.64%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 13.64%
Nausea (feeling of having an urge to vomit): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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