Ranolazine and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranolazine (ranolazine) and Imdur (isosorbide mononitrate). Common drug interactions include hypotension among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Ranolazine and Imdur. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

92 people who take Ranolazine and Imdur together, and have interactions are studied.

What are the common drug interactions of Ranolazine and Imdur, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Abdominal pain upper
Adverse drug reaction
Asthenia (weakness)
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Chronic kidney disease
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Face injury

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Hypotension (abnormally low blood pressure)
Dizziness
Blood pressure decreased
Cardiac failure
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death
Fall
Hallucination (an experience involving the perception of something not present)
Hypersensitivity

What are the common drug interactions of Ranolazine and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infection
Laryngeal injury
Neck injury
Road traffic accident
Chest pain
Erythema (redness of the skin)
Feeling hot
Flushing (the warm, red condition of human skin)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

Stent placement
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Back pain
Cardiac failure congestive
Coronary arterial stent insertion
Coronary artery bypass
Diastolic dysfunction
Disability
Fluid retention (an abnormal accumulation of fluid in the blood)

60+:

Chest pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Headache (pain in head)
Injury
Cardiac failure congestive
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Anaemia (lack of blood)
Arthralgia (joint pain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Stable Angina (a constant chest pain): 45 people, 48.91%
High Blood Pressure: 14 people, 15.22%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 11.96%
Chest Pain: 9 people, 9.78%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 7.61%
Type 2 Diabetes: 5 people, 5.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 5.43%

* Approximation only. Some reports may have incomplete information.

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