Ranolazine and Nitro-dur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranolazine (ranolazine) and Nitro-dur (nitroglycerin). Common drug interactions include chest pain among females and coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ranolazine and Nitro-dur. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

What is Nitro-dur?

Nitro-dur has active ingredients of nitroglycerin. eHealthMe is studying from 2,414 Nitro-dur users. Check the latest studies of Nitro-dur.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

16 people who take Ranolazine and Nitro-dur together, and have interactions are studied.

Ranolazine and Nitro-dur drug interactions.

What are the common drug interactions of Ranolazine and Nitro-Dur, by gender? *:

female:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Epistaxis (bleed from the nose)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Dizziness
  6. Asthenia (weakness)
  7. Cardiac failure congestive
  8. Carotid artery disease
  9. Carotid artery occlusion (artery blockage)
  10. Carotid artery stenosis (narrowing of carotid artery)

male:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Stent placement
  3. Chest discomfort
  4. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  7. Colonic polyp (extra part of colon tissue grow in intestine)
  8. Deafness
  9. Death
  10. Diabetic foot

What are the common drug interactions of Ranolazine and Nitro-Dur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Stent placement

60+:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
  4. Asthenia (weakness)
  5. Back pain
  6. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  7. Cardiac failure congestive
  8. Carotid artery disease
  9. Carotid artery occlusion (artery blockage)
  10. Carotid artery stenosis (narrowing of carotid artery)

What are the existing conditions these people have? *

  1. Chest Pain: 12 people, 75.00%
  2. Stress And Anxiety: 11 people, 68.75%
  3. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 68.75%
  4. Oedema (fluid collection in tissue): 10 people, 62.50%
  5. High Blood Pressure: 10 people, 62.50%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 62.50%
  7. Restless Leg Syndrome (a powerful urge to move your legs): 10 people, 62.50%
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 62.50%
  9. High Blood Cholesterol: 10 people, 62.50%
  10. Weight Decreased: 9 people, 56.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ranolazine and Nitro-dur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ranolazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nitro-dur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ranolazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitro-dur and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ranolazine and nitroglycerin (the active ingredients of Ranolazine and Nitro-dur, respectively), and Ranolazine and Nitro-dur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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