Rapamune and Trandate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rapamune (sirolimus) and Trandate (labetalol hydrochloride). Common drug interactions include renal failure among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Rapamune and Trandate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

What is Trandate?

Trandate has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,735 Trandate users. Check the latest studies of Trandate.

On Jul, 02, 2026

11 people who take Rapamune and Trandate together, and have interactions are studied.

Rapamune and Trandate drug interactions.

What are the common drug interactions of Rapamune and Trandate, by gender? *:

female:

Renal failure (kidney dysfunction)
Aplasia (defective development or congenital absence of an organ or tissue)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Respiratory distress (difficulty in breathing)
Viral infection
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Headache (pain in head)
Kidney transplant rejection
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Tongue oedema (swelling of tongue)

male:

Abdominal pain
Blood potassium decreased
Thrombocytopenia (decrease of platelets in blood)
Diarrhoea
Graft dysfunction
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Proteinuria present
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Rapamune and Trandate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplasia (defective development or congenital absence of an organ or tissue)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Respiratory distress (difficulty in breathing)
Viral infection

20-29:

n/a

30-39:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Headache (pain in head)
Kidney transplant rejection
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Tongue oedema (swelling of tongue)

40-49:

Graft dysfunction
Thrombocytopenia (decrease of platelets in blood)
Proteinuria present
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Taste disturbance
White blood cell count increased
Abdominal pain
Blood potassium decreased
Complications of transplanted kidney

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Thrombocytopenia (decrease of platelets in blood): 2 people, 18.18%
Hypertensive Crisis: 2 people, 18.18%
Hyperglycemia (high blood sugar): 2 people, 18.18%
Sleep Disorder: 1 person, 9.09%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 1 person, 9.09%
Muscle Aches (muscle pain): 1 person, 9.09%
Joint Pain: 1 person, 9.09%
Haematuria (presence of blood in urine): 1 person, 9.09%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 9.09%
Abdominal Pain: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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